10 citations
,
January 2014 in “Journal of Mid-life Health” This article reviews dermatological problems associated with estrogen deficiency in menopausal women and highlights the importance of dermatologist and gynecologist collaboration, but reports no new clinical results.
September 2024 in “Pigment Cell & Melanoma Research” This study found that mitochondrial fusion regulator Opa1 is crucial for maintaining melanocyte stem cells during the hair follicle cycle in mice, with Opa1 deficiency leading to impaired SCF-KIT signaling, reduced melanocyte populations, and early hair graying.
September 1993 in “Archives of Disease in Childhood” This article discusses the importance of considering biotin deficiency in diagnosing neurological, dermatological, or respiratory illnesses linked to hair loss, and reports no new research results.
March 2025 in “Frontiers in Plant Science” This study highlights the ZmNF-YC1-ZmAPRG pathway as a potential mechanism to improve maize tolerance to phosphorus deficiency, emphasizing its role in modulating lipid and photosynthetic activity, although direct impacts on root adaptations remain unclear (Bai et al., 2024).
81 citations
,
November 2012 in “Journal of the National Cancer Institute” This study found that FLCN deficiency in mice muscles led to increased mitochondrial biogenesis and a metabolic shift towards oxidative phosphorylation, with a similar advantage observed in FLCN-null kidney cancer cells.
June 2026 in “Quality in Sport” This narrative review analyzed the literature on premature hair graying, identifying potential contributors such as nutrient deficiencies, oxidative and emotional stress, smoking, genetic factors, autoimmune diseases, and medication side effects, but reported no effective treatment to reverse it, underscoring the necessity for further research.
This study observed that vitamin D deficiency is linked to a weakened immune system and may promote autoimmune inflammation in individuals with diffuse alopecia, where hair loss happens throughout the scalp.
27 citations
,
April 2020 in “Journal of Experimental Botany” This study found that glutathione deficiency affects lateral root and root hair responses to indole butyric acid in plants, but not to indole acetic acid, indicating its role in auxin pathway regulation.
33 citations
,
April 2002 in “Journal of Cutaneous Medicine and Surgery” This review discusses the skin conditions linked to eating disorders and emphasizes that treating the underlying disorder often improves these dermatological symptoms.
16 citations
,
February 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.
7 citations
,
February 2017 in “Open veterinary journal” This study suggests that deficiencies in certain amino acids, like taurine and tryptophan, in artificial milk formulas may contribute to skin and eye problems in Bengal tiger cubs.
1 citations
,
August 2012 in “Pediatrics in review” This paper reviews various vitamin deficiencies, including vitamin D, and highlights their potential health impacts. It does not report new research findings but discusses current recommendations and risks associated with these deficiencies.
1 citations
,
February 2009 in “Journal of Investigative Dermatology” This study found that VEGF-deficient keratinocytes can form tumors using different aneuploidy and signaling patterns, highlighting VEGF's role beyond angiogenesis in tumor cell growth and survival.
March 2023 in “Photodiagnosis and Photodynamic Therapy” This study found that vitamin D levels were lower in alopecia areata patients, with trichoscopic features like broken hairs and black dots more prevalent in cases with vitamin D deficiency.
2 citations
,
October 1961 in “Experimental Biology and Medicine” This study found that rabbits fed a diet deficient in Vitamin E developed severe muscular dystrophy that was not fully prevented by adding selenium, Vitamin E supplements, or natural feedstuffs, indicating other nutritional deficiencies.
139 citations
,
February 2014 in “Journal of Advanced Research” This review explores the impact of vitamin D deficiency on the skin from a dermatological perspective, but reports no new clinical results.
48 citations
,
July 2002 in “Journal of Cutaneous Medicine and Surgery” This review discusses the variety of skin conditions linked to eating disorders and emphasizes that resolving these skin issues often requires treating the underlying disorder.
10 citations
,
February 2015 in “Clinics in Dermatology” This article discusses various periocular conditions like madarosis, milphosis, trichomegaly, and dermatochalasis, and highlights their potential link to underlying local and systemic diseases, but reports no new clinical findings.
1 citations
,
August 2013 in “The Journal of Cell Biology” This study found that Wnt secretion is important for skin homeostasis in mice, as Evi-deficient mice developed skin lesions resembling psoriasis and showed immune cell imbalance.
1 citations
,
March 2005 in “Trends in Endocrinology and Metabolism” Androgens affect behavior, hair, bones, muscles, and the heart, and can be used to treat certain conditions.
December 2016 in “Journal of Evolution of Medical and Dental Sciences” This case report highlights that inherited zinc deficiency can persist into adulthood and emphasizes the importance of selecting optimal chelating agents to improve oral zinc bioavailability.
82 citations
,
September 1983 in “Clinics in Gastroenterology” Zinc is vital for health, and its deficiency can worsen gastrointestinal and liver diseases.
19 citations
,
November 1937 in “Experimental biology and medicine” This study reports that distinct scaly dermatoses in rats can be caused by deficiencies in vitamin H, vitamin B6, or lactoflavin, each preventable or treatable through nutritional adjustments.
16 citations
,
January 1995 in “Dermatology” This case report discusses chronic mucocutaneous candidiasis with autoimmune and immune deficiencies in candidiasis-endocrinopathy syndrome, noting associated alopecia areata, ineffective topical immunotherapy, and asplenia.
4 citations
,
December 2022 in “Frontiers in Endocrinology” This review discusses various treatment options for non-classic congenital adrenal hyperplasia due to 21α-hydroxylase and 11β-hydroxylase deficiencies without providing new clinical results.
1 citations
,
June 2023 in “Nutrients” This study found that women with polycystic ovary syndrome had deficient or suboptimal serum vitamin D levels, but the effects of vitamin D on metabolic syndrome and hormonal balance remain unclear.
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This research discusses a zebrafish model showing that nicastrin deficiency leads to tyrosinase-dependent depigmentation and melanophore cell death, suggesting implications for studying skin depigmentation disorders.
2 citations
,
January 2018 in “International Journal of Trichology” This case report describes trichothiodystrophy in two sisters with only hair fragility, illustrating the condition's variable presentation and the importance of regular monitoring for potential associated impairments.
This article reviews the role of hormones in human penis development and associated conditions due to hormonal imbalances, but reports no new findings, suggesting hormone replacement can manage some conditions.
37 citations
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October 2021 in “Nutrients” This study discusses the potential association between low vitamin D levels and insulin resistance, suggesting that vitamin D deficiency may contribute to disorders like obesity and diabetes, but emphasizes the need for further research to confirm these links.