Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this case study, drospirenone use masked the diagnosis of a rare form of congenital adrenal hyperplasia, suggesting a possible delay in detecting underlying endocrinopathies.

This article reviews the potential causes of insufficient androgen action during fetal development, such as enzyme and receptor gene mutations or environmental disruptors, but reports no new results.

This study found that the expression of androgen receptors is higher in the scalp area affected by androgenetic alopecia, and its expression varies based on different traditional Chinese medicine syndromes.

This review discusses the use of zinc in treating dermatological conditions and concludes that, aside from systemic zinc deficiency, its efficacy as a primary treatment is unproven, though it may be useful as a supplementary therapy.

This study found that patients with alopecia areata exhibit a stronger deficiency in coping with stress compared to those with androgenetic alopecia and controls, suggesting a psychosomatic component to the condition.

In a retrospective cohort of patients with steroid 5 α-reductase 2 deficiency, this study identified seven novel genetic variants in the SRD5A2 gene, expanding the variant database and contributing to improved diagnostic and therapeutic approaches for the condition.

This study discusses zinc's vital role in skin cell growth and how its deficiency can lead to acrodermatitis enteropathica, marked by symptoms like alopecia and dermatitis. It notes that similar symptoms appear in people with certain metabolic conditions, referred to as acrodermatitis dysmetabolica.

This study found a correlation between reduced serum ferritin levels and specific alopecia patterns in female patients, suggesting a potential role of iron deficiency in conditions like telogen effluvium and female pattern hair loss.

This review highlights that malnutrition, including deficiencies in proteins and micronutrients, may exacerbate allergic conditions like dermatitis and asthma by promoting inflammation, while adequate micronutrient intake supports regulatory immune responses.

In this study, researchers observed that deficiency in biochemical markers, notably ferritin and serum iron, is frequently found in female patients diagnosed with telogen effluvium, suggesting these tests are crucial in understanding and treating the condition.

No specific results were reported in this abstract; it aims to explore the psychological effects of hair loss conditions like Chronic Telogen Effluvium and Androgenetic Alopecia, emphasizing the potential link between micronutrient deficiency and hair health.

This study found that men with androgenetic alopecia had significantly lower serum vitamin D levels compared to controls and the deficiency strongly correlated with the severity of the condition.

In this study, physicians diagnosed a 3-year-old with scurvy due to severe vitamin C deficiency, influenced by a vegan diet and potential early-stage celiac disease; after treatment with vitamin C supplementation, her condition rapidly improved, highlighting the importance of dietary considerations in pediatric health.

This paper offers a detailed overview of B vitamins, detailing their importance for energy, cognition, and metabolism, conditions leading to their deficiencies, symptoms of deficiencies, and the foods rich in these essential nutrients.

This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.

This research observed that the skeletal abnormalities in Noggin null mice varied based on genetic background, and identified haploinsufficiency leading to joint fusions, similar to human conditions associated with NOGGIN deficiency.

In this study, mini rats with reduced growth hormone and insulin-like growth factor-1 levels exhibited distinct differences in skin thickness and hair cycle compared to standard Wistar rats, suggesting potential use as an animal model for studying GH deficiency-related skin conditions.

This study found significant reductions in zinc, copper, and iron levels in patients with idiopathic telogen effluvium compared to healthy controls, suggesting a potential role for trace element deficiency in the condition.

In this report, researchers describe a 13-month-old with neurodevelopmental disorder NEDESBA, confirming a TRAPPC4 gene mutation as the cause after excluding biotinidase deficiency, highlighting the importance of molecular testing for accurate diagnosis in overlapping metabolic and genetic conditions.

This case report highlights an atypical presentation of acrodermatitis enteropathica in an 18-year-old male, exhibiting symptoms like erythrokeratoderma variabilis with a positive response to high-dose oral zinc, underscoring the importance of considering zinc deficiency in unusual skin conditions.

This review suggests that the mTOR signaling pathway may play a significant role in hair follicle health by influencing the effects of Vitamin D receptor deficiency, potentially contributing to hair follicle damage and related hair loss conditions.

In this study, researchers created a mouse model using CRISPR/Cas9 technology to investigate hypotrichosis simplex and woolly hair, finding that Krt71-knockout mice exhibited curly hair and developed complete hair shedding without immune deficiencies, mimicking conditions seen in humans and potentially aiding future hair disorder research.

This study reports a unique case of coinheritance of BRCA2 and CYLD pathogenic variants in a man with metastatic malignant cylindroma, suggesting that recognizing such genetic profiles in rare conditions can provide new treatment options, including the potential use of therapies targeting BRCA deficiency.

This study found that a school-based nutritional program improved adolescents' waist measurements, blood counts, and reduced rates of certain skin and mucosal conditions associated with vitamin deficiency.

This study identified a new genotype, V281+I172N/V281L, linked to non-classical 21-hydroxylase deficiency, suggesting it should be considered in genetic panels for the condition.

Low levels of ferritin and vitamin B12 are common in women with telogen effluvium, but the link between nutrient deficiencies and the condition is not clear.

This study found that women with telogen effluvium had significantly lower serum copper and zinc levels compared to controls, suggesting these deficiencies may be associated with the condition.

This study found that patients with alopecia areata had lower serum zinc and biotin levels compared to healthy controls, suggesting these deficiencies may play a role in the condition's pathogenesis.

In this case report, a 33-year-old male with symptoms resembling Neuromyelitis Optica was treated with 10 mg biotin daily, which may reverse certain ophthalmologic and myelopathy findings. The researchers emphasize the need for further research on biotinidase deficiency in patients misdiagnosed with similar conditions.

In this case-control study, individuals with alopecia areata showed significantly elevated levels of inflammatory markers IL-4, IFN-γ, and CRP, as well as reduced serum Folate and Ferritin, suggesting the condition's multifactorial pathophysiology involves immune activation, systemic inflammation, and micronutrient deficiencies.