December 2023 in “Journal of family medicine and primary care” This study focused on understanding the psychosocial impact of androgenetic alopecia in Saudi Arabia to potentially improve treatment strategies for hair loss by incorporating stress-coping methods and new therapeutic approaches.
20 citations
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February 2022 in “British Journal of Dermatology” This study found that people with alopecia areata have higher rates of depression and anxiety, leading to increased mental health treatment burden, more time off work, and higher unemployment compared to the general population.
1 citations
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July 2025 in “Journal of the National Medical Association” This study observed that patients newly diagnosed with alopecia areata frequently experience mental health issues, with anxiety and depression being the most common, highlighting the importance of integrated medical and psychological care for these individuals.
July 2024 in “International Journal of Molecular Sciences” This article proposes using the hallmarks of ageing and dysregulated microRNAs to create a molecular morbidity score that could improve prognostication and clinical trial inclusion for patients with multimorbidity.
November 2025 in “Annals of Dermatology” This study found a strong positive correlation between alopecia areata burden and the Socio-Demographic Index, indicating a disproportionate impact on high-income countries, especially affecting young adults and females.
March 2022 in “Women's health issues” This review highlights the urgent need for increased research and policy support for autoimmune and immune-mediated skin diseases, which are on the rise and disproportionately affect women's health in the United States, suggesting a focus on gender and socioenvironmental factors.
February 2026 in “Archives of Dermatological Research”
This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.
December 2025 in “The Journal of Clinical Psychiatry” Finasteride is not proven to cause depression or suicide, and careful patient monitoring is advised.
December 2022 in “Dermatology and Therapy” This review discusses the unmet needs and barriers in managing alopecia areata in Latin America, highlighting access constraints and recommending coordinated efforts to improve patient outcomes with promising new treatments.
4 citations
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July 2022 in “Journal of health economics and outcomes research” This review discusses the economic burden of alopecia areata in adolescents and reports no new results; the authors note that evidence in this area is limited.
May 2026 in “Frontiers in Pharmacology” This study found that long-term use of 5α-reductase inhibitors is associated with improved overall survival in men with renal cell carcinoma, particularly those with low comorbidity not receiving surgery or systemic therapy, suggesting a potential role for androgen modulation in disease management.
15 citations
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January 2018 in “Acta dermato-venereologica” This study found that dermatological treatments significantly reduce health-related quality of life among patients with various skin conditions, suggesting that the burden of these therapies should be considered in treatment planning and development.
12 citations
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June 2024 in “Archives of Dermatological Research” This scoping review found a high prevalence of skin conditions among older people living at home, but available evidence on burden and effective care strategies is limited.
1 citations
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August 2023 in “Acta dermato-venereologica” This study found that corticosteroids were the most common treatments for alopecia areata in the USA, but the substantial disease burden suggests a need for more effective options.
December 2025 in “Cureus” This study found that post-COVID syndrome symptoms persisted and were more common in individuals who had recovered from COVID-19 compared to uninfected controls in Kerala, though both groups showed significant symptom burdens.
17 citations
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January 2022 in “Annals of Dermatology” In this study, the severity of pediatric alopecia areata was found to decrease the quality of life for both patients and their families while increasing the overall burden.
September 2023 in “Acta dermato-venereologica” This study found that pilonidal sinus disease is a common comorbidity with hidradenitis suppurativa and is linked with increased disease severity, suggesting it may serve as a sentinel event for identifying high-risk patients.
95 citations
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August 2022 in “JAMA Network Open” This study documented an increased health care burden due to post-COVID conditions in the 6 months following the acute phase of infection, providing vital evidence for resource planning.
September 2018 in “Value in Health” In this study, researchers found that in Germany, orphan drugs with a phase III study and no comparable treatments available tend to receive higher HTA scores. There was no significant correlation between HTA scores and orphan drug prices or discount rates.
4 citations
,
July 2024 in “The Journal of Dermatology” This study found that patients with alopecia areata in Dubai experience significant disease and economic burdens, especially when comorbid with psychological conditions, despite frequent dermatologist consultations and topical steroid prescriptions.
May 2023 in “Journal of managed care & specialty pharmacy” This review discusses the pathophysiology, economic burden, and treatment options of alopecia areata and reports no new clinical results, highlighting the need for better therapies, including JAK inhibitors.
October 2023 in “Dermatologie pro praxi” This source outlines the autoimmune condition alopecia areata, discussing its unclear etiology, the significant psychological impact despite not being life-threatening, and the challenging nature of its treatment, which varies greatly among individuals. The article summarizes disease pathogenesis, prevention, and treatment options.
1 citations
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April 2025 in “Skin Appendage Disorders” This study found that patient-reported alopecia areata severity is associated with scalp and facial hair loss as well as emotional and financial burdens, suggesting that factors beyond just scalp hair loss should be considered.
20 citations
,
November 2012 in “Journal der Deutschen Dermatologischen Gesellschaft” This review examines psychosomatic hair diseases, discussing their classification, implications, and the need for tailored psychosomatic therapy, without reporting new clinical results.
1 citations
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February 2025 in “Frontiers in Medicine” This study found that patients with juvenile-onset systemic lupus erythematosus have a high prevalence of endocrine and metabolic comorbidities, particularly dyslipidemia and obesity-related issues, suggesting the need for routine monitoring and obesity prevention.
March 2024 in “Dermatology and therapy” This study analyzed data from 2083 patients with alopecia areata in Europe and found that those with atopic, autoimmune, or psychiatric comorbidities encountered more severe disease and were more likely to require advanced treatments compared to those without comorbid conditions.
3 citations
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May 2018 in “Experimental Dermatology” In this study, the researchers reported that patient impacts and symptoms of hidradenitis suppurativa, as assessed by HSIA and HSSA measures, are associated with clinical characteristics such as the number of abscesses and inflammatory nodules.
139 citations
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December 2021 in “Journal of Clinical Medicine” This systematic review reports that fatigue was the most common symptom in both phases of long COVID, with lung function issues more frequent in the ongoing symptomatic phase and psychological burdens like anxiety and depression more prevalent in the post-COVID syndrome phase.
32 citations
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June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This systematic review found that long COVID symptoms, particularly fatigue, sleep disorder, and dyspnoea, were similarly prevalent in ongoing symptomatic COVID-19 and post-COVID-19 syndrome, but psychological issues and poor quality of life were more common in the latter.