114 citations
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March 2021 in “Scientific Reports” This study found that, among COVID-19 patients in South Korea, hypertension, diabetes, and other comorbidities significantly increased mortality risk, with the age-adjusted Charlson comorbidity index being a strong predictor of death.
August 2020 in “Research Square (Research Square)” This study found that an age-adjusted Charlson comorbidity index of four or more strongly predicts mortality in South Korean COVID-19 patients, highlighting the impact of comorbidity burden and older age on disease severity.
10 citations
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March 2023 in “Journal of Managed Care & Specialty Pharmacy” This study found that patients with alopecia areata had similar total health care costs as those with atopic dermatitis, despite having fewer comorbidities and prescription medications overall.
February 2025 in “PubMed” This study found that although the global incidence of alopecia areata has risen since 1990, age-standardized rates have slightly decreased, with significant comorbidity associations varying by region.
March 2025 in “Meditsinskiy sovet = Medical Council” This study reviewed literature and assessed clinical data on treating alopecia areata linked with atopic diseases, finding that therapies like dupilumab, phototherapy, and JAK inhibitors may address overlapping symptoms, suggesting a focus on reducing pharmacological burden and enhancing quality of life.
April 2012 in “Journal of the American Academy of Dermatology” This study found that psoriasis patients had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to those without psoriasis.
July 2026 in “Journal of Investigative Dermatology” This retrospective cohort study found that individuals with alopecia totalis or universalis have a higher prevalence of systemic autoimmune diseases, particularly endocrine diseases and inflammatory bowel disease, compared to those with patchy alopecia areata.
1 citations
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July 2021 in “Journal of the American Academy of Dermatology” Hospitalizations for atopic dermatitis are more due to other health issues now, not the condition itself.
This study found that patients with psoriasis have a significantly higher prevalence of autoimmune diseases and other physical and mental comorbidities compared to those without the condition.
This study found that patients with psoriasis had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to individuals without psoriasis.
18 citations
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October 2020 in “PLoS ONE” This study highlights the interconnected emotional distress between patients with end-stage COPD and their family caregivers, emphasizing that both parties' functional and emotional variables influence each other's distress.
9 citations
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January 2022 in “Dermatology” This review reports a notably higher prevalence and severity of alexithymia among dermatology patients than healthy controls, suggesting its consideration may enhance treatment outcomes and quality of life.
23 citations
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July 2021 in “Advances in Therapy” This study observed that patients with alopecia areata often have comorbidities and experience significant healthcare costs, with treatments like systemic therapies being infrequently used.
12 citations
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April 2022 in “Dermatology and therapy” This study reports that patients with alopecia areata in the US incur significantly higher healthcare utilization and expenses, primarily driven by ambulatory and pharmacy costs, compared to matched controls.
1 citations
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September 2022 in “JMIR dermatology” In this study, Canadian patients with alopecia areata and their caregivers reported a significant negative impact on their quality of life, including high feelings of self-consciousness, anxiety, and risk of adjustment disorder.
September 2025 in “Dermatology and Therapy” This study reviewed the burden of alopecia areata in the UAE, noting limited regional data on patient demographics and treatments but highlighting the approval and promising results of the Janus kinase inhibitor baricitinib for managing this condition.
July 2025 in “Dermatology and Therapy” This study found that patients with alopecia areata showing low treatment burden responded better to baricitinib compared to those with higher previous systemic treatment exposure.
2 citations
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November 2025 in “Frontiers in Immunology” In this study, researchers highlighted the high global prevalence of immune-related skin diseases like dermatitis and psoriasis, noting that females are disproportionately affected, emphasizing the need for tailored public health strategies based on sex and region.
144 citations
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” This review reports that alopecia areata affects about 2% of people globally and is linked with psychiatric and medical comorbidities, highlighting its significant disease burden.
2 citations
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July 2025 in “Scientific Reports” In this study, researchers found that dermatological diseases like atopic dermatitis, psoriasis, and hidradenitis suppurativa impact women's work performance and daily activities more severely than men's, with women reporting higher absenteeism and work impairment and lower work ability scores.
January 2026 in “Frontiers in Medicine” This review identified evidence gaps in NHIRD, emphasizing the lack of validated diagnostic criteria and the need for further research on ocular and systemic comorbidities associated with AA to enhance patient care and treatment strategies.
April 2026 in “Health Sciences Quarterly” In this single-center study, researchers conducted comprehensive dermatological exams of 112 hospitalized adult patients, revealing that several skin issues, like seborrheic dermatitis and xerosis cutis, were common but often unnoticed in routine hospital care, highlighting the need for better dermatology collaboration.
February 2026 in “Frontiers in Public Health” This study identified that while the overall burden of AA among adolescents and young adults globally continues to rise, the age-standardized rates have slightly decreased, with notable disparities across age, gender, region, and socioeconomic status.
79 citations
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March 2017 in “Dermatologic clinics” This review discusses the complex systemic nature of vitiligo and its associations with autoimmune conditions, emphasizing the need for increased understanding and awareness of related comorbidities and psychological effects.
11 citations
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November 2021 in “BMJ Open” This study reviews the epidemiology of alopecia areata in the UK, focusing on its links to mental health comorbidities, autoimmune/atopic associations, and common infection incidences.
1 citations
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April 2025 in “Dermatology and Therapy” This study identified three patient groups based on the psychological and social impact of vitiligo, with the most affected group experiencing severe psychosocial burdens despite often having mild physician-reported disease severity.
6 citations
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July 2022 in “Journal of health economics and outcomes research” This study found that US adolescents with alopecia areata, especially those with alopecia totalis or universalis, experience significantly higher healthcare costs and resource use compared to matched controls.
September 2018 in “Value in Health” This study found that the prevalence of statin users in South Korea increased annually by 12%, with those having comorbidities like coronary disease and diabetes incurring higher medical costs.
10 citations
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January 2023 in “Journal of the European Academy of Dermatology and Venereology” This review highlights the significant negative impact of alopecia areata on quality of life, mental health, and work, calling for individualized approaches and effective treatments to mitigate these effects.
April 2025 in “PharmacoEconomics - Open” This study observed that patients with AA showed a high willingness to trade off lifespan for better disease-specific quality of life, indicating a significant disease burden.