March 2026 in “Dermatology Online Journal” In this study, androgenetic alopecia was linked to a higher likelihood of hyperlipidemia in both men and women and obesity in women, highlighting it as a potential marker for cardiometabolic risk.
February 2026 in “Skin Appendage Disorders” This study found a significant association between pseudofolliculitis barbae and mood disorders such as depression and anxiety, but not with obsessive-compulsive disorder.
February 2026 in “Boletín Médico del Hospital Infantil de México” This study suggests pediatric patients with alopecia areata may benefit from screening for atopic, autoimmune, and psychiatric comorbidities to enable timely identification and treatment.
November 2025 in “Journal of Clinical Medicine” This review article explores the potential systemic nature of alopecia areata, highlighting the association with ocular abnormalities and suggesting that shared pathogenic pathways may lead to eye symptoms occurring at younger ages than usual.
October 2025 in “Dermatology and Therapy” This study reviewed the literature on atopic dermatitis and found a strong connection with several other skin conditions, such as psoriasis and alopecia areata, while highlighting potential treatments like JAK inhibitors and dupilumab that show promise for these comorbidities.
August 2025 in “Dermatology and Therapy” This study found that among US adults with vitiligo, the most prevalent autoimmune comorbidities were thyroid disease and alopecia areata, with evidence suggesting greater vitiligo extent increases prevalence of several autoimmune conditions.
386 citations
,
April 2006 in “PubMed” This review discusses the prevalence and treatment of benign prostatic hyperplasia and reports no new findings; it emphasizes considering side effects and comorbidities in therapy choices.
49 citations
,
January 2018 in “Immunology” This review discusses the relationship between psoriasis and autoimmunity, focusing on autoimmune co-morbidities, but reports no new research findings.
34 citations
,
March 2015 in “Clinical and Experimental Dermatology” This study observed that patients with pemphigus have a higher incidence of hypothyroidism, inflammatory bowel disease, and diabetes compared to the general population.
23 citations
,
April 2017 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the importance of recognizing and treating psychiatric conditions in dermatology patients, offering practical recommendations for dermatologists to manage psychocutaneous diseases effectively, but reports no new clinical results.
5 citations
,
August 2024 in “Frontiers in Immunology” In this study, upadacitinib was reported as effective in rapidly treating psoriasiform eczema in five male patients and showed varying degrees of effectiveness on other immune-mediated comorbidities like alopecia areata, vitiligo, ulcerative colitis, and hidradenitis suppurativa.
4 citations
,
March 2025 in “Pediatric Dermatology” This review examines the clinical presentation of alopecia areata in children and compares it to adult-onset cases, noting that data on pediatric cases is scarce and often varies, with reported onset typically between ages 6 and 12.
4 citations
,
February 2024 in “Biomedicine” The authors concluded that specific comorbidities and complications increase the risk of severe COVID-19 and impede patient recovery, making them critical factors to control in order to lessen the disease's adverse effects.
3 citations
,
May 2025 in “Archives of Gynecology and Obstetrics” In this study, researchers reported that women with polycystic ovary syndrome in a German-speaking population had higher probabilities of depression, anxiety, sleep disorders, and obstructive sleep apnea, all associated with BMI and insulin resistance.
2 citations
,
May 2025 in “Journal of Clinical Medicine” This study reported that in a case series of three adolescents with alopecia areata and atopic dermatitis, treatment with 15 mg/day of upadacitinib led to rapid improvement in skin symptoms and significant hair regrowth over 12 months, with no severe adverse events observed.
1 citations
,
August 2025 in “Journal of Diabetes and its Complications” This review found that among young adults with type 1 diabetes, hearing loss prevalence ranged from 22.6% to 48.0% and was associated with age, diabetes duration, and systolic blood pressure, while peridontitis and alveolar bone loss also showed varying prevalence patterns.
1 citations
,
February 2025 in “Frontiers in Medicine” This study found that patients with juvenile-onset systemic lupus erythematosus have a high prevalence of endocrine and metabolic comorbidities, particularly dyslipidemia and obesity-related issues, suggesting the need for routine monitoring and obesity prevention.
1 citations
,
January 2022 in “Medical Science” This study found that patients with Alopecia Areata, particularly those with severe forms, exhibited higher triglycerides, cholesterol, and low-density lipoproteins, suggesting increased cardiovascular risk factors.
September 2023 in “International journal of women’s dermatology” This study found mixed evidence linking traction hairstyles, previous pregnancies, chemical hair relaxers, and several comorbidities to an increased risk of central centrifugal cicatricial alopecia in Black women.
April 2023 in “JAAD international” This study observed that among a Moroccan population with frontal fibrosing alopecia, common comorbidities included lichen planus pigmentosus (36.8%), rosacea (28.9%), thyroid disorders (23.7%), and dyslipidemia (21.1%), highlighting potential relationships mediated by shared inflammatory or metabolic pathways.
April 2019 in “Journal of Investigative Dermatology” This study suggests that hormone replacement therapy and oral contraception may have a protective role in scarring alopecia, as these were reported less frequently by patients with the condition compared to those with female pattern hair loss.
18 citations
,
February 2018 in “Journal of the American Academy of Dermatology” This study reports no new clinical results but suggests a potential relationship between frontal fibrosing alopecia and cutaneous conditions such as rosacea, indicating a need for further research.
5 citations
,
January 2017 in “Dermato-endocrinology” This study found that postmenopausal women with a history of hirsutism and/or oligo-amenorrhea have a higher prevalence of several comorbidities, including heart and respiratory diseases, than those without these reproductive history markers.
2 citations
,
September 2023 in “Journal of the American Academy of Dermatology”
1 citations
,
October 2023 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that, in Germany between 2016 and 2020, alopecia areata had an annual prevalence of 210 cases per 100,000 and an incidence of 72 cases per 100,000, with higher rates in specific regions and associated with comorbidities like atopic dermatitis and psoriasis.
1 citations
,
June 2023 in “Cureus” In this study, researchers found that among adolescent and adult female patients with seborrheic dermatitis, 60.9% had cutaneous comorbidities like acne, while 28.3% had systemic comorbidities such as diabetes mellitus, though not all associations were statistically significant.
1 citations
,
April 2023 in “Archives of Dermatological Research” This study proposes a grading system based on comorbidities and systemic involvement to assess the severity of dermatological emergencies.
January 2026 in “SKIN The Journal of Cutaneous Medicine” This systematic review found that patients with androgenetic alopecia have an elevated prevalence of psychiatric conditions, which may increase their susceptibility to post-finasteride syndrome symptoms.
September 2024 in “Journal of the American Academy of Dermatology”
August 2023 in “Journal of the American Academy of Dermatology” This study found no significant difference in comorbidities between patients with central centrifugal cicatricial alopecia and those with nonscarring alopecia.