100 citations
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July 2018 in “Journal of The American Academy of Dermatology” This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.
92 citations
,
January 2013 in “Dermatology” This study reports a high prevalence of comorbid autoimmune conditions, particularly thyroid disorders and psoriasis, among vitiligo patients in Boston teaching hospitals.
56 citations
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March 2017 in “Journal of the American Academy of Dermatology” Alopecia areata patients often have eczema, thyroid issues, vitamin-D deficiency, and anemia.
47 citations
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May 2020 in “Cardiovascular Research” This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.
9 citations
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November 2018 in “Dermatologic Clinics” This review highlights recent literature on comorbidities in dermatologic diseases, emphasizing the need for further research into connections between atopic dermatitis and pancreatic cancer, and pemphigus diseases and COPD, but it reports no new clinical results.
8 citations
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July 2020 in “Journal of The American Academy of Dermatology” Patients with Lichen Planopilaris are more likely to have rosacea and skin cancer but less likely to have congestive heart failure, stroke, and glaucoma.
7 citations
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April 2021 in “Journal of The American Academy of Dermatology” This study reported that the incidence of telogen effluvium nearly tripled during the pandemic, with significant increases in Hispanic and non-White populations, and suggested comorbidities combined with COVID-19 positivity may raise the risk.
4 citations
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January 2025 in “JAAD reviews.” This literature review found that pediatric patients with vitiligo may have increased risks of conditions such as atopic dermatitis, alopecia areata, autoimmune thyroid disease, and psychiatric disorders, impacting their quality of life. Screening should consider these risks for effective management.
October 2024 in “Skin Appendage Disorders” This study found that lichen planopilaris is associated with several environmental factors, such as stress and hair dye use, as well as thyroid disorders and genetic components.
November 2023 in “Medical Immunology (Russia)” In this study, researchers found that children with alopecia areata exhibited immune system imbalances, including increased autoimmune and allergic markers and decreased phagocytic activity, along with a higher prevalence of autoimmune thyroiditis and allergic rhinitis compared to children without alopecia.
March 2026 in “Dermatology and Therapy” This study found that patients with discoid lupus erythematosus have a high prevalence of systemic, cardiometabolic, endocrine, and psychiatric comorbidities, with significant associations to conditions such as cardiovascular disease and depression.
August 2025 in “Frontiers in Immunology” This study found that patients with primary cicatricial alopecia are at higher risk of developing various comorbidities, including systemic lupus erythematosus, hypothyroidism, and dermatological conditions, compared to controls.
March 2025 in “JEADV Clinical Practice” In this retrospective chart review, researchers found that patients with scarring alopecia, including central centrifugal cicatricial alopecia, have a higher prevalence of various systemic comorbidities, such as vitamin D deficiency and metabolic syndrome, compared to the general US population.
January 2024 in “Dermatologic therapy” This review describes the characteristics and treatment of acne keloidalis nuchae, focusing on related conditions and available therapeutic approaches, but presents no new clinical findings.
November 2023 in “International Journal of Dermatology” In this study, CCCA patients were found to have higher odds of metabolic, autoimmune, atopic, and psychiatric comorbidities compared to matched controls.
September 2022 in “Dermatology and therapy” This review discusses the pathological factors and comorbidities associated with androgenetic alopecia and reports no new clinical results, emphasizing the need for improved understanding and treatment in clinical practice.
This study found that early-onset androgenetic alopecia is associated with higher prevalence of metabolic syndrome, atheroma plaques, and urinary symptoms related to prostate growth compared to controls.
January 2019 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, chronic telogen effluvium and female pattern hair loss were the most common types of non-scarring diffuse hair loss among Indian women aged 15-45, with anemia frequently present across cases.
66 citations
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March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.
22 citations
,
August 2020 in “Journal of the American Academy of Dermatology” Women with lichen planopilaris and frontal fibrosing alopecia often have other health issues like hypothyroidism and lupus.
19 citations
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April 2018 in “International Journal of Dermatology” This study found that female patients with frontal fibrosing alopecia are significantly more likely to have systemic lupus erythematosus compared to controls.
17 citations
,
October 2020 in “Journal of Clinical Medicine” In this study, Koreans with rosacea showed higher odds of experiencing various systemic comorbidities, including autoimmune diseases and certain cancers, compared to controls.
6 citations
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May 2024 in “Clinical and Experimental Dermatology” According to this systematic review, children with alopecia areata experience significant psychosocial impacts, including anxiety, depression, and lower self-esteem, which are exacerbated by increased disease severity and affect quality of life, academic performance, and social interactions.
4 citations
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July 2024 in “The Journal of Dermatology” This study found that patients with alopecia areata in Dubai experience significant disease and economic burdens, especially when comorbid with psychological conditions, despite frequent dermatologist consultations and topical steroid prescriptions.
2 citations
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January 2018 in “Annals of Dermatology” This review discusses the potential association between androgenetic alopecia and metabolic syndrome, and notes AGA might be linked to arterial stiffness; it reports no new clinical findings and calls for further research.
1 citations
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January 2024 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that ocular comorbidities, particularly errors of refraction, are common in patients with Alopecia Areata, but dermoscopic findings are not predictive of these ocular issues.
August 2026 in “Acta Dermato Venereologica” This study found that women with central centrifugal cicatricial alopecia had a substantial prevalence of systemic comorbidities, including strong associations with dyslipidemia, uterine leiomyomas, and anxiety disorders.
July 2026 in “Dermatology and Therapy” This study highlights that dissecting cellulitis of the scalp affects a diverse racial population and is associated with male sex, metabolic dysfunction, and psychiatric comorbidities, challenging its traditional characterization as primarily a disorder of Black men.
June 2026 in “British Journal of Dermatology” This study found that individuals with frontal fibrosing alopecia have increased odds of thyroid disease, lupus erythematous, vitiligo, and heart disease, supporting the consideration of FFA as a systemic disorder.
April 2026 in “Boletín Médico Del Hospital Infantil de México (English Edition)” This study found that 90% of pediatric patients with alopecia areata had comorbidities, including allergic rhinitis and atopic dermatitis, with localized AA being associated with better treatment outcomes and fewer relapses compared to non-localized forms.