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    Glossary Collagen Synthesis

    process of creating collagen, crucial for skin and hair structure

    Collagen synthesis, also known as collagen formation or collagen production, is the process by which the body produces collagen, a vital protein that provides structure and strength to skin, hair, nails, bones, and connective tissues. This process involves the assembly of amino acids into procollagen, which is then modified and assembled into mature collagen fibers, essential for maintaining the integrity and elasticity of various tissues.

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    1. The 800-nm diode laser irradiation induces skin collagen synthesis by stimulating TGF-β/Smad signaling pathway Lasers in Medical Science · 2011 · 59 citations
    2. Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An in vitro and in vivo Study Clinical, cosmetic and investigational dermatology · 2020 · 34 citations
    3. Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin International Journal of Molecular Sciences · 2025 · 1 citations
    4. Determination of proliferation and collagen synthesis of human dermal hair papilla cells Linchuang pifuke zazhi · 2004 · 1 citations
    5. Fermented rice bran extract delays skin aging by increasing the synthesis of collagen and elastin Frontiers in Pharmacology · 2025
    6. Phenytoin or Spironolactone Intervention Counteracts 5-Fluorouracil–Induced Alopecia in Rats by Suppressing Oxidative Stress and Inflammation While Promoting Collagen Synthesis Preprints.org · 2025
    7. Silk fibroin hydrogel with recombinant silk fibroin/NT3 protein enhances wound healing by promoting Type III collagen synthesis and hair follicle regeneration in skin injury Materials Today Bio · 2025
    8. Collagen-type synthesis in human-hair papilla cells in culture Archives of Dermatological Research · 1988 · 28 citations
    9. AP collagen peptides improve hair growth and quality by promoting human hair cell proliferation and keratin synthesis Archives of Biological Sciences (Beograd) · 2024
    10. Inhibitory effects of bFGF, VEGF and minoxidil on collagen synthesis by cultured hair dermal papilla cells Archives of Dermatological Research · 1996 · 3 citations
    11. The Effects of X-irradiation on Collagen Metabolism in Rat Skin International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · 1976 · 11 citations
    12. Effects of Polygoni Multiflori Radix on the Elastase, and Collagenase Activities and the Procollagen Synthesis in Hs68 Human Fibroblasts The Korea Journal of Herbology · 2014 · 2 citations
    13. Expression of melanocortin receptors on cutaneous fibroblastic cells – collagen and beyond Experimental Dermatology · 2005 · 1 citations
    14. Prospects of Collagen Stimulating Injections for Antiaging International Journal of Applied Pharmaceutics · 2026
    15. Multi-Omics Reveals That Hydroxypinacolone Retinoate Alleviates UV-Induced Skin Aging via the p38/MMP9/Collagen Axis Clinical Cosmetic and Investigational Dermatology · 2026
    16. [Three-dimensional culture of plucked human hair follicles inside the collagen gel matrix]. PubMed · 1990 · 3 citations
    17. Synthesis of Sericin based Stretchable and Self-healing Hydrogel Loaded with <i>Psidium guajava</i> L. Extract for Treatment of Burn Wound Journal of Burn Care & Research · 2026
    18. Alterations of collagen type 1, skin fibroblasts, and macrophages in the scalp following the treatment of 1550‐nm erbium glass fractional laser for androgenetic alopecia Journal of Cosmetic Dermatology · 2021
    19. Sustainable and Green Zinc Oxide Nanoparticle Synthesis from Zingiber Officinale as a Wound Healing Accelerator The Egyptian Journal of Medical Microbiology · 2025
    20. Design of an artificial skin. IV. Use of island graft to isolate organ regeneration from scar synthesis and other processes leading to skin wound closure Journal of Biomedical Materials Research · 1998 · 13 citations
    21. Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects International journal of biological macromolecules · 2018 · 269 citations
    22. The human tri-peptide GHK and tissue remodeling Journal of biomaterials science. Polymer ed. · 2008 · 165 citations
    23. Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration Stem Cell Research & Therapy · 2022 · 148 citations
    24. Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging International Journal of Molecular Sciences · 2017 · 132 citations
    25. Nutraceuticals: A Review Dermatology and Therapy · 2018 · 95 citations
    26. Effect of discarded keratin-based biocomposite hydrogels on the wound healing process in vivo Materials Science and Engineering C · 2015 · 89 citations
    27. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018 · 68 citations
    28. Suppression of fibroblast proliferation and lysyl hydroxylase activity by minoxidil. Journal of Biological Chemistry · 1987 · 63 citations
    29. Use of silicon for skin and hair care: an approach of chemical forms available and efficacy 2016 · 45 citations
    30. Macrophages are necessary for skin regeneration during tissue expansion Journal of Translational Medicine · 2019 · 44 citations