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90-120 / 1000+ resultsresearch Corticotropin releasing hormone and the skin
This review discusses the role of corticotropin-releasing hormone in human skin, focusing on its regulation, receptors, and functions, and highlights parallels with the hypothalamo-pituitary-adrenal axis; it reports no new research findings.
research From Hair to Cornea: Toward the Therapeutic Use of Hair Follicle-Derived Stem Cells in the Treatment of Limbal Stem Cell Deficiency
This study found that stem cells from mouse hair follicles successfully reconstructed the ocular surface in most limbal stem cell deficiency mice, demonstrating potential for treating the condition in a mouse model.
research Complex Regional Pain Syndrome I (Reflex Sympathetic Dystrophy)
This review examines current knowledge and treatment strategies for complex regional pain syndrome type I in adults, emphasizing clinical aspects and highlighting the lack of consensus on therapeutic approaches, without presenting new clinical findings.
research Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion
This study found that overexpression of PKCα in mouse epidermis increases expression of specific proinflammatory mediators and induces inflammation but does not significantly affect epidermal differentiation, proliferation, or tumor promotion with TPA.
research Hair growth stimulated by conditioned medium of adipose-derived stem cells is enhanced by hypoxia: evidence of increased growth factor secretion
This study found that subcutaneous administration of conditioned medium from adipose-derived stem cells promoted hair growth in mice, and hypoxia enhanced this effect by altering growth factor secretion.
research A preliminary observation: Male pattern hair loss among hospitalized COVID‐19 patients in Spain – A potential clue to the role of androgens in COVID‐19 severity
Male pattern hair loss could hint at androgens affecting COVID-19 severity.
research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
This review discusses the modern approach of skin tissue engineering for chronic wound treatment, focusing on bioengineered artificial skin substitutes and assessing innovations in biomaterials and cell use; it reports no new clinical results.
research Comparison of stratum corneum penetration and localization of a lipophilic model drug applied in an o/w microemulsion and an amphiphilic cream
This study found that an oil-in-water microemulsion of curcumin penetrated deeper into the human stratum corneum and hair follicles compared to an amphiphilic cream.
research COVID-19: Pulmonary and Extra Pulmonary Manifestations
This study concluded that COVID-19 is a multisystem disease with both pulmonary and extrapulmonary manifestations, underscoring the importance of considering these symptoms for early diagnosis and infection control.
research Methimazole, Carbimazole, and Congenital Skin Defects
Methimazole may cause skin defects in babies if taken during pregnancy.
research Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals
This study found that differentiated cells of the corneal epithelium can be converted to hair and interfollicular epidermis through a multistep process involving dermal developmental signals.
research Integrated analysis of coding genes and non-coding RNAs during hair follicle cycle of cashmere goat (Capra hircus)
This study identified potential ceRNA regulatory networks in cashmere goat hair follicle cycling, expanding understanding of lncRNA and miRNA biology and annotation of the goat genome.
research Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers
This study developed a framework to handle missing participant data in systematic reviews for continuous outcomes, finding varied impacts on confidence in effect estimates across reviewed cases.
research Incorporation of Isotopically Labeled Cocaine and Metabolites into Human Hair: 1. Dose-Response Relationships
This study suggests that while hair analysis using GC-MS is a sensitive method for detecting cocaine ingestion, it may not reliably indicate the amount, timing, or duration of drug use due to interindividual variability and multiple incorporation mechanisms.
research Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats
This study found that transcriptome profiling of cashmere goat skin revealed key genes and pathways involved in hair follicle initiation, differentiation, and maturation, which are critical for improving fleece production.
research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents
This review examines regenerative hair waves and complex hair cycle domains in transgenic mice, highlighting how these dynamic processes contribute to skin regeneration and the physiological regulation of organs, but reports no new experimental results.
research Patient factors influencing dermal filler complications: prevention, assessment, and treatment
This review discusses best practices for minimizing complications with dermal fillers and provides guidance based on expert consensus, yet it reports no new clinical results.
research Type XVII collagen coordinates proliferation in the interfollicular epidermis
This study found that COL17 deficiency in neonatal mice causes abnormal skin cell proliferation due to disrupted Wnt signaling, while replenishing or overexpressing COL17 can reverse this effect in both neonatal and aged skin.
research Comparison of finasteride (proscar®), a 5α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5α reductase inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research COVID-19 in adult patients with pre-existing chronic cardiac, respiratory and metabolic disease: a critical literature review with clinical recommendations
This review discusses the disproportionate negative impact of the COVID-19 pandemic on individuals with chronic medical conditions and calls for strategies to protect these vulnerable populations.
research Maternal Influence on Child HPA Axis: A Prospective Study of Cortisol Levels in Hair
This study observed that cortisol concentrations in hair, indicating prolonged stress, are correlated between mothers and young children, suggesting potential heritable traits or maternal influence.
research Effects of shampoo and water washing on hair cortisol concentrations
In this study, washing rhesus monkey hair with water or shampoo significantly reduced cortisol levels, suggesting potential underestimation of chronic stress hormone deposition in hair due to washing.
research Androgenetic alopecia present in the majority of patients hospitalized with COVID-19: The “Gabrin sign”
This study observed a high prevalence of androgenetic alopecia in patients hospitalized with severe COVID-19, with 79% of men and 42% of women affected, suggesting a potential link between androgen sensitivity and COVID-19 severity.
research Role of macrophages in collagen resorption during hair growth cycle
Macrophages help break down collagen around hair follicles during hair growth.
research COVID-19 vaccines while pregnant or breastfeeding
This study highlights that the ACIP strongly recommends COVID-19 vaccination and booster doses for pregnant women, those breastfeeding, or trying to conceive, due to the safety of non-live vaccines in these groups and the protection they also offer to infants.
research MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling
This study found that the protein MIM is crucial for maintaining cilia and Sonic hedgehog signaling in mesenchymal cells by counteracting Src-mediated phosphorylation of Cortactin, impacting hair follicle formation.
research PULSED ADMINISTRATION OF CORTICOSTEROIDS IN THE TREATMENT OF ALOPECIA AREATA
This study found that monthly oral prednisolone pulses of 300 mg were effective and safe for treating widespread alopecia areata, with 58.3% of patients achieving cosmetically acceptable hair growth.
research Efficacy and safety of a new clobetasol propionate 0.05% foam in alopecia areata: a randomized, double‐blind placebo‐controlled trial
In this study, clobetasol propionate foam demonstrated effectiveness and good patient compliance as a safe topical treatment for moderate to severe alopecia areata, with significant hair regrowth compared to placebo.
research Postinflammatory hyperpigmentation: a common but troubling condition
Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.