104 citations
,
May 2003 in “Endocrinology” This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.
93 citations
,
April 2003 in “Proceedings of the National Academy of Sciences of the United States of America” This study identified an unexpected critical role for the FATP4 protein in skin and hair development in mice, linking it to a potential candidate gene for restrictive dermopathy in humans.
41 citations
,
December 1988 in “Journal of Investigative Dermatology” 35 citations
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October 2002 in “Biochemical and Biophysical Research Communications” This study reports that K7 expression patterns observed in mice are similar to those in humans, revealing previously unreported expression in the gastrointestinal tract, tongue, and various "hard" epithelial tissues.
26 citations
,
February 1998 in “Chemico-Biological Interactions” This review discusses recent molecular biology advances in the human phenol sulfotransferase gene family and reports no new results; the authors highlight its relevance for studies of endogenous and xenobiotic metabolism.
25 citations
,
September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” This study concludes that rhesus macaques are a suitable model for testing the pharmacological properties of finasteride and other 5aR inhibitors, due to their biochemical similarity to humans.
1 citations
,
January 2012 In this study, the researchers cloned and analyzed the CRABP I gene in Inner Mongolian cashmere goats, finding its highest mRNA expression at 90 days in embryo skin compared to later stages.
1 citations
,
April 1983 in “Trends in Biochemical Sciences”
November 2023 in “Scientific reports” This study presents the first report on cloning and characterizing the full-length cDNA of SRD5A1 in Indian catfish (Clarias magur), revealing expression differences across reproductive phases and increased expression post-Ovatide administration in ovaries and testis.
January 2013 in “Heilongjiang xumu shouyi” This study successfully cloned the KAP6.1 gene from Xinjiang fine-wool sheep and found its genetic sequence has high homology with sheep and goat sequences, indicating close genetic relationships.
January 2010 in “Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi” This study found that epithelial stem cells from umbilical skin can differentiate into various cell types, suggesting potential roles in epidermis and hair cell formation.
January 2010 in “Acta Laboratorium Animalis Scientia Sinica” This research reports that the ultra-high sulfur keratin promoter acts as a tissue-specific promoter in mouse hair follicles, as shown by induced expression of GFP and β-gal in that region post-transfection.
March 1998 in “Journal of Dermatological Science” Keratin-associated proteins may have roles in various mouse tissues, not just hair.
September 2025 in “Chemical Engineering Journal” This study found that poly(butylene citramalate-co-butylene succinate) copolymers exhibit high toughness, recyclability, degradability, and biocompatibility, achieving complete wound healing with skin and hair follicle regeneration in 7 days.
February 2024 in “arXiv (Cornell University)” In this study, researchers found that differences in skin condition distribution are the main source of errors when AI algorithms classify dermatological conditions from new, previously unseen sources, and proposed steps to improve their generalizability based on available information.
39 citations
,
August 1998 in “FEBS Letters” In this study, researchers identified two novel peptidylarginine deiminases from treated rat keratinocytes, both showing enzyme activity with PAD‐R11 reflecting a characteristic of epidermal enzymes.
32 citations
,
November 1998 in “Journal of Biological Chemistry” This study found that the unique functions of keratin 16 are likely determined by its tail domain, challenging the previous hypothesis about the role of the helix 1B subdomain.
18 citations
,
November 2016 in “PeerJ” This study found that hair follicles can be used to generate pluripotent stem cells, which successfully differentiate into keratinocytes and may improve hair regeneration and grafting for medical applications.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses follicular cell implantation as a potential solution for hair restoration limitations, but notes inconsistencies and challenges in human applications, reporting no new clinical results.
11 citations
,
October 2014 in “Gene” In this study, researchers characterized the FGF5 gene in Chinese Merino sheep, identified a new mRNA splicing variant, FGF5S, and noted its restricted expression in the brain, spleen, and skin.
2 citations
,
February 2014 in “Animal Biotechnology” This study reported that the PTGER2 gene is strongly expressed in cashmere goat skin and its expression tends to decrease from the anagen to telogen stages of the hair follicle cycle.
2 citations
,
March 2013 in “Hair transplant forum international” This article discusses the concept of hair cloning through cultured follicular cell implantation but provides no new experimental results; it highlights ongoing interest among hair restoration professionals and the public.
1 citations
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March 2022 in “Hair transplant forum international” This review discusses potential strategies for rejuvenating miniaturizing hair follicles in androgenic alopecia but reports no new clinical results; it explores the idea of using DHT-resistant follicle preservation for long-term hair maintenance.
1 citations
,
October 2010 in “2010 3rd International Conference on Biomedical Engineering and Informatics” This study successfully cloned and characterized the LEF-1 gene from Inner Mongolia Cashmere Goats, potentially aiding efforts to enhance cashmere production through genetic modification.
1 citations
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January 2010 in “Springer eBooks” This article discusses hair cloning as a potential solution to the limited availability of donor hair in transplantation, but it reports no new results.
This study found that human hair follicles can be used to generate induced pluripotent stem cells, which can then efficiently differentiate back into keratinocytes.
October 2015 in “CRC Press eBooks” This article reviews the concept of using cell therapy for hair loss treatment, emphasizing the ongoing development of methods to create and implant hair follicles in vitro but reports no new findings.
January 2014 in “Hair transplant forum international” This abstract omits specific findings and does not provide new research results.
January 2012 in “Journal of Northwest A & F University” In this study, the researchers observed that Eda mRNA expression in goat skin peaks during the catagen phase of the hair cycle, suggesting its involvement in hair cycle regulation.
January 2007 in “Journal of Inner Mongolia University” This study achieved successful cloning of the ovine keratin associated protein 6-1 gene, which may facilitate future research on transgenic animals and hair follicle gene regulation.