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Finasteride reduces prostate size and PSA levels in young patients.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Finasteride cream reduces hair growth in women with hirsutism, but more research needed.