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This study discusses advancements in nanotechnology and theranostic dressings, which may significantly improve chronic wound care by effectively targeting biofilms and enabling real-time monitoring, although obstacles to broad applicability and sustainability remain.

In this case study, PRP and PRF treatments helped achieve complete healing of chronic wounds, including a chemical burn ulcer in three weeks and a pilonidal sinus post-incision in eight weeks, suggesting potential benefits for chronic wound management.

This review discusses recent advances in wearable bioelectronics for the monitoring and management of chronic wounds and reports no new results; the authors highlight potential benefits but emphasize existing challenges and future research needs.

This study found that increasing the levels of specific microRNAs from the miR-17∼92 cluster improved wound healing in mice by reducing inflammation, suggesting a potential therapeutic approach for chronic wounds.

This review highlights that the RNA modification N⁶-methyladenosine (m⁶A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.

This study suggests that DcR3 can reprogram macrophages towards a reparative state, enhancing wound healing and hair follicle regeneration, making it a potential target for treating chronic wounds and alopecia.

This study reviews advancements in the use of biodegradable polymers for wound healing, highlighting various polymer formulations and the observed enhancement of processes like cell proliferation and wound healing in both in-vitro and in-vivo experiments.

This review covers skin manifestations in chronic kidney disease, highlighting their impact on quality of life, associated prognostic indicators, and available treatments, but provides no new clinical results.

This review reports that chitosan-based systems with metal nanoparticles and polyphenols may enhance wound healing by improving the bioavailability and stability of these compounds, suggesting a potential new approach for chronic and diabetic wounds.

In this study, researchers developed a versatile sprayable hydrogel that promotes wound healing in mice by facilitating rapid gelation, reducing inflammation, and accelerating tissue regeneration, with potential applications in chronic wound treatment and beyond.

This review discusses wound healing options after skin excision and laser treatments for hidradenitis suppurativa and reports no new clinical results.

This review synthesizes the latest advances in wound healing and scar management, exploring molecular mechanisms, therapeutic strategies, and providing an evidence-based comparison of topical agents like Dermatix Ultra and Contractubex for scar improvement, aimed at informing clinicians and patients in decision-making.

This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.

This review highlights promising recent advances in therapies for epidermolysis bullosa, including gene therapy and stem cell approaches, but reports no definitive cures and emphasizes the need for further research.

In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.

This review discusses various biomedical applications of hyaluronic acid, highlighting its roles in cancer treatment, wound healing, inflammation control, antibiotics, and antioxidant functions, with an emphasis on recent developments and potential for advanced drug delivery and tissue repair systems.

This study found that using hair follicle units to treat hard-to-heal wounds led to complete or partial closure in most patients, with reduced operation time, minimal morbidity, and low complication rates and costs.

This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.

The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

This review discusses the role of microRNAs in skin function and potential therapeutic applications, emphasizing their importance in wound healing and disease management, though it reports no new experimental findings.

This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.

This review discusses various potential applications of platelet-rich fibrin in dermatology, but reports no clinical results and highlights the need for standardized protocols.

This article reviews the effectiveness of adrenal cortex compounds E and F in treating various connective tissue disorders and reports no new clinical findings.

This review discusses current wound management strategies and examines electrospun nanofibers with biological macromolecules for their potential in tissue engineering and drug delivery, but reports no new clinical results.

In this study, solid lipid microparticles loaded with lidocaine hydrochloride were developed to effectively deliver pain relief and antimicrobial benefits for wound management, demonstrated by testing with bioengineered skin substitutes and showing effectiveness against common wound-infecting bacteria.

This review categorizes contractile hydrogels by their contraction mechanisms and explores their role in advanced wound management, emphasizing mechanical and biochemical signaling in healing, but also notes challenges like force transmission and clinical applicability.

In this case study, the researchers reported that surgical debridement combined with targeted dermatological and antimicrobial therapy effectively managed chronic lower-limb wounds in a patient with keratitis-ichthyosis-deafness syndrome, underscoring the importance of a multidisciplinary approach in treating this rare condition.

In diabetic mice, this study reported that the multifunctional hydrogel CPGel achieved complete wound closure in 21 days, showing promise in improving chronic wound healing through antibacterial, antioxidative, and tissue regeneration properties.

This study demonstrated that a multifunctional hydrogel containing Prussian blue nanozymes and an ultrasound-responsive nitric oxide donor improved healing in diabetic wounds by reducing oxidative stress, promoting angiogenesis, and enhancing tissue repair in animal models.

This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.