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Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

No true link between AGA and insulin resistance, but coexistence may worsen AGA.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Ethnic differences in hair and skin are significant and under-researched, requiring tailored dermatologic treatments and more study.

Minoxidil and spironolactone slow hair loss in women.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.

A woman with CHILD syndrome showed skin abnormalities, and the report suggests CHILD nevus and NEVIL might be the same condition, highlighting the need for diagnosis for genetic advice.

A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.

Surgery on a baby with a skin disorder improved eyelid position and eye health.

Men with common hair loss (AGA) are more likely to have metabolic syndrome, which increases heart disease risk. Early screening could help prevent heart disease. More research is needed to understand this relationship better.

Found new possible treatments for hair loss.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.