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Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Many women with PCOS have undiagnosed health issues and show different symptoms based on the clinic they visit.

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Hibiscus rosa-sinensis may help treat various health issues and promote hair growth, but more research is needed for safety.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

Consider benefits and risks of new alopecia treatments for safety.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Poor sleep is linked to a higher risk of developing and worsening urinary problems in men.

People with alopecia areata have higher insulin resistance.

Five Weimaraners had a milder form of color dilution alopecia causing hair loss and skin issues.

Itraconazole helps improve tough skin infections but may not prevent them from coming back.

COVID-19 may harm male fertility and damage the reproductive system.

The document concludes that more research is needed to fully understand the causes of PCOS.