55 citations
,
October 1992 in “Archives of Dermatology” In this study, researchers observed that loose anagen hair syndrome is an autosomal dominant disorder characterized by abnormal hair follicle structure and premature keratinization, possibly due to signaling and desmosomal component disturbances.
41 citations
,
September 2007 in “Pediatric emergency care” This review discusses the challenges in diagnosing tinea capitis and highlights the need for laboratory confirmation and systemic treatment due to the limited effectiveness of topical antifungals; no new clinical results are presented.
40 citations
,
September 2018 in “Journal of the American Academy of Dermatology” This letter discusses the emerging use of Janus kinase inhibitors, specifically oral tofacitinib, for treating alopecia areata in children, but reports no new clinical findings.
36 citations
,
October 2016 in “Medical mycology” This study at Mbarara University of Science and Technology found that T. violaceum is the most common cause of tinea capitis in children in Western Uganda, and systemic therapy is preferred over topical treatments for effective management due to the nature of the infection.
35 citations
,
December 2009 in “Lupus” This study found that parental reports of neuro-psychiatric disorders were higher in children exposed to maternal anti-Ro antibodies, yet these differences compared to controls were not statistically significant.
32 citations
,
December 1969 in “The Lancet” This study found a significant shift to the telogen phase in the hair growth of children with classical marasmus compared to normal children, suggesting a connection to the chronicity of the condition.
26 citations
,
March 1981 in “Clinical Endocrinology” In this study, researchers found that oestrogen did not increase adrenal androgen secretion in children with premature adrenarche or in adolescents with gonadal dysgenesis undergoing oestrogen replacement therapy.
23 citations
,
November 1986 in “Pediatrics” Minoxidil, when used with a diuretic and β-blocking agent, can safely lower blood pressure in most children with severe hypertension due to kidney disease, with minimal side effects.
17 citations
,
April 2023 in “British Journal of Dermatology” This study suggests that off-label use of baricitinib in children under 12 with alopecia areata may improve hair regrowth, but further research is needed to confirm efficacy and safety.
15 citations
,
January 2022 in “Journal of Infection” This study's meta-analysis found that COVID-19 vaccines are effective and safe for children, with inactivated vaccines showing the highest effectiveness and causing less injection site pain compared to attenuated vaccines.
14 citations
,
March 2007 in “Pediatric pulmonology” This study found evidence suggesting that hypertrichosis may be an adverse effect of inhaled corticosteroids in children, although it does not always resolve after stopping treatment.
13 citations
,
December 2020 in “PLoS ONE” This study found dependencies between genetic variants and various phenotypes related to fetal and early childhood growth and neurological development in healthy infants, suggesting significant gene candidates for further investigation.
12 citations
,
November 2018 in “Psychoneuroendocrinology”
12 citations
,
March 2015 in “Pediatric Dermatology” This review discusses diagnostic and management challenges of polycystic ovary syndrome in children and adolescents and reports no new clinical results; it emphasizes early intervention when a provisional diagnosis is suspected.
11 citations
,
March 2002 in “Pediatric Dermatology” Temporal triangular alopecia is a non-scarring hair loss seen in some Asian children.
11 citations
,
November 1966 in “Experimental Biology and Medicine” This study suggests hair diameter may indicate protein status in children if the sampling location on the head is controlled, noting inconsistencies in past research.
9 citations
,
December 2020 in “British Journal of Dermatology” This research letter reports that low-dose oral minoxidil improved hair density and length in children with loose anagen hair syndrome.
8 citations
,
August 2016 in “Expert opinion on pharmacotherapy” This review discusses current and future treatments for alopecia areata and trichotillomania in children and reports no new clinical results, emphasizing the need for safer and more effective therapies.
8 citations
,
August 2013 in “Pediatric Dermatology” This article reviews loose anagen hair syndrome, an inheritable hair disorder affecting children and sometimes adults, but does not report any new clinical results.
7 citations
,
July 2021 in “JAAD case reports” This review discusses the potential of dupilumab for treating alopecia areata, reporting mixed outcomes with both improvement and new-onset hair loss observed in case reports.
7 citations
,
March 2018 in “Journal of The American Academy of Dermatology” This study found that pediatric HSCT recipients, especially those with chronic graft-versus-host disease, are at risk for developing various nonmalignant late cutaneous changes such as vitiligo, psoriasis, alopecia, and nail changes.
6 citations
,
July 2019 in “Indian Journal of Dermatology” This study found that tinea capitis was the most common cause of scalp hair loss in children, affecting over half of cases, followed by alopecia areata, seborrheic dermatitis, and other conditions.
6 citations
,
November 2007 in “Archives of Disease in Childhood: Education & Practice” This review discusses common causes of alopecia in children, such as telogen effluvium and alopecia areata, and highlights diagnostic and therapeutic challenges, but presents no new clinical results.
5 citations
,
December 2021 in “Pediatric investigation” In this study, children with 5-alpha-reductase deficiency and micropenis treated with oral testosterone undecanoate showed increased penile length to a target level after 3-9 months, with no severe adverse effects observed, suggesting the treatment's safety and efficacy.
5 citations
,
July 2019 in “Nutrients” This study found that boys in Mexico City with selenium intake below the recommended dietary allowance had lower odds of progressing to advanced stages of pubertal development, while no association was observed in girls.
4 citations
,
February 2022 in “JEADV Clinical Practice” This review discusses the diverse range of skin manifestations in children with COVID-19 and highlights the complexity of clinical assessment due to varied presentations; it reports no new clinical findings.
4 citations
,
January 2019 in “PubMed” This study found that low dose valproate monotherapy in epileptic children commonly leads to side-effects like weight gain and decreased appetite, especially among younger patients.
3 citations
,
October 2024 in “Advances in Therapy” In this study, Chinese children with central precocious puberty receiving 6-monthly injections of triptorelin showed luteinizing hormone suppression and slowed development of sexual characteristics over 12 months, without severe adverse events, suggesting it may be an effective treatment option for this population.
3 citations
,
November 2021 in “Applied Microscopy” This article presents a comprehensive overview of hair microscopy techniques and their diagnostic potential for systemic and cutaneous disorders, emphasizing its usefulness in resource-limited settings and highlighting the underutilization of this non-invasive method due to lack of awareness.
3 citations
,
January 2017 in “Journal of Pakistan Association of Dermatology” This study observed that tinea capitis is prevalent among school children in Karachi, with T. violaceum as the most common organism and asymptomatic carriers possibly facilitating its spread.