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This study investigated different centrifugation systems and found that low-speed protocols and certified centrifuges produced better-quality platelet-rich fibrin and recommended using FDA-approved glass tubes for safe and effective regenerative outcomes.

This study found that PRP injections, prepared using a digital centrifuge with a large-sized sodium citrate tube at low centrifugation speed, significantly improved hair thickness and terminal hair percentage in women with pattern hair loss, with similar results across different preparation methods.

This study reviews current methods for making and using platelet-rich plasma and fibrin, emphasizing the variability in clinical outcomes due to differences in preparation protocols, and calls for standardized guidelines and large-scale studies for better effectiveness in regenerative medicine.

This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.

This review examines how different centrifugation protocols for preparing platelet-rich plasma may affect platelet concentration, integrity, growth factor content, and ultimately clinical outcomes, but reports no new clinical results.

This study found that a centrifugation protocol of 1300 rpm/246 g for 20 minutes followed by 1600 rpm/373 g for 20 minutes achieved the highest platelet yield in platelet-rich plasma.

In this in vitro study, simple centrifugation with calcium gluconate activation led to a significantly higher release of PDGF-BB in PRP compared to other methods, which may inform improved clinical PRP preparation protocols.

In this systematic review and meta-analysis, the authors examined single-spin versus double-spin centrifugation protocols for PRP in patients with androgenic alopecia and found no significant difference in platelet concentration, hair density, or hair types between the protocols.

In this systematic review and meta-analysis, the researchers found no significant difference in platelet concentration, hair density improvement, or changes in terminal and vellus hair rates between single-spin and double-spin PRP centrifugation protocols in treating androgenic alopecia.

This article describes a protocol for using bioengineered techniques to regenerate functional hair follicles and their stem cell niches by manipulating epithelial and mesenchymal cells.

This review analyzes studies on autologous platelet-rich plasma for androgenic alopecia, reporting mixed results and highlighting the need for standardized protocols and further research.

This review found that while platelet-rich plasma shows potential benefits for hair restoration, there is a lack of standardized preparation and treatment protocols, necessitating further rigorous trials.

This letter comments on a randomized controlled trial by Shapiro et al that found no significant benefits of platelet-rich plasma compared to placebo for male androgenetic alopecia, highlighting issues with PRP protocol variations.

This study suggests that platelet-rich plasma may provide short-term improvement in hair density for female pattern hair loss, but results varied and more rigorous trials are needed to establish optimal protocols.

This study found that in a specific setup, the syringe method of platelet-rich plasma preparation was more effective for platelet increment and sterility compared to the tube method.

This narrative review evaluates the diverse preparation methods and uses of platelet-rich plasma across various indications and concludes how well current evidence supports its effectiveness in each case, but reports no new clinical findings.

AA-PRP temporarily increases hair density in androgenetic alopecia but loses effectiveness over time.

This study concluded that using Plasma gel and PRP as autologous collagen biostimulators improved acne scars and skin density, demonstrating efficiency and safety for facial rejuvenation in clinical evaluations including patient satisfaction.

This review highlights that autologous platelet concentrates, particularly platelet-rich fibrin, have shown potential to enhance healing and outcomes in both dental and medical applications, including injury recovery and aesthetics.

This study found significant variability in the production and use of platelet-rich plasma and related products in Brazil, highlighting the need for regulatory measures to ensure safety.

This study found that using a centrifugation speed of 1800 rpm for 10 minutes is optimal for preparing platelet-rich plasma with PRPBAG®, yielding an eightfold increase in platelet concentration.

This review examines various methods for purifying extracellular vesicles loaded with drugs, highlighting their principles, benefits, and drawbacks, and stresses the importance of standardized guidelines to enhance the reproducibility of EV-based drug delivery research.

This review discusses the evolution of platelet concentrates in regenerative medicine, highlighting a proposed function-driven classification that distinguishes three generations of PCs by biological activity rather than development order, with third-generation exosome-based therapies showing superior therapeutic efficacy over earlier formulations.

This study found that while MSC concentration in BMCs correlates with total cell counts, cellularity does not indicate high MSC content.

This study found that a combination of betulin and cytostatic Namitecan had a statistically significant synergistic effect on solid Ehrlich adenocarcinoma tumors in NMRI mice, and suggests a promising method for administering betulin in in vivo experiments despite its water insolubility.

This review discusses various mechanical isolation procedures for tissue-like stromal vascular fraction, such as the nanofat procedure, and highlights the need for controlled trials to assess their regenerative effectiveness.

In this study, L-PRF was associated with successful osseointegration and tissue healing when used with biomaterial for dental implants in a patient with an atretic bone ridge.

This review discusses the use, efficiency, and preparation methods of autologous platelet concentrates in wound healing and periodontal regeneration, but it reports no new clinical findings.

This review discusses the use of platelet-rich plasma as a treatment for androgenetic alopecia and highlights the need for standardized protocols, reporting no new clinical results.

In this book, the authors provide an accessible overview of platelet concentrates and their dental applications, highlighting their role in tissue healing and regeneration, and reviewing recent studies on their efficacy in periodontal therapy, implant dentistry, and oral surgery.