December 2023 in “The journal of cell biology/The Journal of cell biology” This study developed the mTurquoise2-Col4a1 mouse model and used fluorescent tagging of collagen IV to offer new insights into basement membrane dynamics during hair follicle budding, revealing that basement membranes are flexible and stable structures in developing skin tissue.
November 2023 in “Frontiers in cell and developmental biology” This source reviews mechanisms and existing treatments for hair aging, highlighting factors like oxidative stress and DNA repair defects that affect hair follicle and stem cell function, and discusses research limitations and future directions in the field.
1 citations
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January 1970 This review discusses the structure, expression, regulation, and potential functions of the nuclear receptor coactivator NcoA4 in cancerous and non-cancerous pathologies, but reports no new results.
353 citations
,
November 2014 in “Molecular immunology” This review discusses the immune functions of porcine skin and proposes a classification of dendritic cell subsets based on similarities to human skin, but it reports no new clinical results.
788 citations
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February 2007 in “Nature” This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.
46 citations
,
October 2023 in “Science Advances” In this study, researchers used 3D bioprinting to successfully create engineered skin tissues with hair follicle-like structures, potentially enhancing skin grafts and safety testing for chemical compounds by more closely mimicking natural skin complexity.
43 citations
,
January 2012 in “Biological Research” This review discusses the embryonic origins and characteristics of various stem cell populations in the skin, but it provides no new experimental results.
37 citations
,
May 2018 in “Developmental Biology” This review discusses the role of neural crest stem cell-like states in adult neural crest-derived tissues, suggesting they may contribute to tissue repair by generating new cell types and activating repair programs.
35 citations
,
May 2006 in “Journal of Investigative Dermatology” Monilethrix involves multiple genes affecting hair structure, including DSG4 mutations.
8 citations
,
January 2016 in “Journal of Veterinary Medical Science” This study found that canine adipose-derived mesenchymal stem cell-derived dermal papilla-like tissues promoted new hair follicle formation and increased vascularization in mice, suggesting potential for hair regeneration.
5 citations
,
September 2009 in “Acta Ophthalmologica” This study found that the Meibomian gland shares structural and cytokeratin composition similarities with hair follicles, and plays a role in hyper-keratinisation observed in obstructive Meibomian gland dysfunction.
1 citations
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January 2019 in “Zenodo (CERN European Organization for Nuclear Research)” This anatomical study on Eclipta alba concluded that unique secretory structures in stems and leaves may serve as identifying features of the plant and the Asteraceae family.
January 2012 in “조직공학과 재생의학” This study demonstrated the potential of newly fabricated epithelial cell scaffolds to enhance hair regeneration, showing promise for future alopecia treatments.
January 2004 in “Drug Development and Industrial Pharmacy” This study explored the solubility and crystal structure of GI197111X, a 5-alpha reductase inhibitor for androgenetic alopecia, finding its solubility in Capmul MCM suitable for a soft gel dosage form.
199 citations
,
January 2004 in “The International Journal of Developmental Biology” This review discusses advances in understanding hair and hair follicle structure, gene expression, and molecular signals in hair formation, without reporting new clinical findings.
122 citations
,
June 2002 in “Genes & Development” This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.
112 citations
,
May 2019 in “Pharmacological Research” This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.
105 citations
,
October 2017 in “Stem cells” This review discusses Wnt signaling pathways in skin development and stem cell regulation, highlighting potential interactions with other pathways but reports no new findings.
18 citations
,
April 2014 in “Stem cells” The researchers reported that minor salivary gland stem cells exhibit stem cell characteristics and respond to tobacco-derived carcinogens, implicating the transforming growth factor beta pathway in their maintenance.
18 citations
,
March 2009 in “Experimental Dermatology” This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.
4 citations
,
January 2021 in “Journal of Clinical Medical Research” This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.
2 citations
,
May 2017 in “InTech eBooks” This review discusses the regenerative potential of hair follicle stem cell populations and current approaches to reconstructing folliculogenesis for alopecia therapy, but reports no new clinical results.
The researchers observed that in cichlid fishes with different dental structures, tooth replacement accelerated more than three times following tooth extraction, alongside distinct changes in gene expression and cellular interactions over one week, providing insights into tooth regeneration mechanisms in vertebrates.
January 2026 in “Cutaneous and Ocular Toxicology” This study found that Yangxuebushen Decoction significantly promoted hair regrowth and improved hair follicle structure in a cyclophosphamide-induced alopecia mouse model by reducing inflammation, oxidative stress, and apoptosis.
January 2023 in “Figshare” This review discusses changes in hair follicle characteristics and stem cell dynamics as indicators of aging in mice, noting increased occurrences of white hairs and curved hair follicles at older ages.
January 1994 in “Memorial University Research Repository (Memorial University)” This study suggests that oleosomes in Sesbania nodules are utilized for cell growth and development but are not directly involved in nitrogen fixation.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study observed that treating hair follicles with BM15766 and 7DHC led to structural damage, disrupted cellular organization, reduced expression of key genes and proteins, and increased apoptosis, in contrast to controls, indicating detrimental effects on hair follicle integrity.
October 2025 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study highlighted the significant role of VSM in cochlear aging, suggesting that changes in its structure and composition may contribute to the development of various pathologies, including congenital hearing disorders, while also identifying the need for further research on VCM-associated molecules.
63 citations
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March 2018 in “Experimental Dermatology” This review explores the physiological roles of collagen XVII in the epidermis, its involvement in stem cell maintenance, and its connections with signaling pathways, but it reports no new results.
36 citations
,
September 2013 in “PLoS ONE” This study found that sweat gland stem cells primarily maintain sweat gland homeostasis but can trans-differentiate to aid in epidermal healing and regenerate diverse skin structures under certain conditions.