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This study found that intravenous administration of a shark-derived receptor antibody, 3P17, promoted hair growth in mice by increasing hair matrix cell proliferation and activating leptin-STAT3 signaling, with transdermal leptin delivery enhancing this effect through improved skin penetration.

This review reports that stem cell-based therapies, natural oils, and low-level laser therapy may offer promising and safe alternative treatments for alopecia, although further standardized trials are needed for confirmation.

This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.

Serotonin helps wounds heal faster.

This study observed that stimulating the cholinergic system via muscarinic receptors in dermal papilla cells and other hair-related tissues promoted hair growth, with mechanisms involving the activation of Wnt/β-catenin signalling pathways in cell cultures and increased hair shaft elongation in mouse vibrissae treated with bethanechol.

This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.

In this study, a serum containing Silybum marianum extract, Manganese PCA, and Lespedeza capitata extract improved hair growth and prolonged the anagen phase in a human scalp skin model.

In this study, researchers observed that alopecia areata patients showed higher Th1 and Th2 responses against specific melanogenesis-related protein epitopes, suggesting a role in disease activity and potential targets for diagnostics and therapies.

This review discusses the potential of exosomes and the secretome in stem cell-based regenerative therapies but reports no new experimental findings.

This review explores the complex interactions between hair follicle stem cells and surrounding structures that are essential for understanding hair regeneration, reporting no new experimental results.

This review introduces the morphological and molecular principles of hair follicle development but reports no new experimental results, focusing on recent insights and forming a working hypothesis.

This review discusses the role of androgens in hair follicle regulation and suggests that a better understanding could enhance treatments for conditions like hirsutism and alopecia, but does not present new findings.

This article reviews the potential role of prolactin as a neuroendocrine modulator in skin biology and pathology, discussing its relevance for conditions such as psoriasis and hair growth, but reports no new clinical findings.

This study investigates the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel mouse model but reports no new results, highlighting the need for further research on its function during the hair cycle.

This study suggests that cutaneous lymphadenoma is a distinct benign lymphoepithelial tumor characterized by androgen receptor expression, hair follicle stem cell markers, and common EGFR gene mutations.

This study suggests that oral and topical tacrolimus may effectively treat psoriasis, atopic dermatitis, and hair growth disorders, although results are mostly based on small or animal studies.

This review discusses the mechanisms and potential benefits of platelet-rich plasma therapy for various skin conditions and reports no new clinical findings.

This study developed microneedles loaded with Platycladus orientalis leaf extract to treat androgenic alopecia, finding that they can effectively deliver active ingredients into the dermis, promote hair follicle growth by removing free radicals, and activate the Wnt/β-catenin pathway.

In this study, Platycladus orientalis leaf extract loaded into hyaluronic acid microneedles was found to promote hair follicle growth by enhancing the environment for hair cell proliferation and activating repair pathways, suggesting potential as a treatment for androgenic alopecia.

This case report details a diagnostic challenge in a postmenopausal woman with severe hyperandrogenism where distinguishing between adrenal and ovarian causes was complicated by elevated 17-OH Progesterone and asymmetric ovarian enlargement; pending surgical pathology is expected to guide further management.

This study found that in mice, oral administration of Lactilactobacillus curvatus LB-P9 accelerated hair regrowth and increased hair thickness, hair follicle numbers, and dermal thickness, likely by boosting hair growth factor production and dermal papilla proliferation.

This article is from the ASPS Education Network and does not report any new research findings.

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.

In this study, SMR-2 and SMR-6, retinoid analogs, were found to be approximately 100 times more toxic than retinoic acid in male mice, primarily affecting skin, immune, and reproductive systems.

This study observed that the herbal extract WJWE promoted hair growth and protected hair follicle cells in a DHT-induced murine model of androgenetic alopecia, potentially by engaging the SIRT1/JNK/p38 MAPK and Wnt5A/β-Catenin signaling pathways.

This study suggests that oleanolic acid may promote hair growth in mice with testosterone-induced androgenetic alopecia by activating the Wnt/β-catenin pathway and influencing various molecular levels.

This study observed that epidermal growth factor significantly enhanced the growth of dermal papilla, dermal sheath cells, and fibroblasts in vitro, particularly benefiting dermal sheath cells.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

This review discusses the roles and mechanisms of tissue-resident regulatory T cells in immune regulation and tissue homeostasis, but reports no new experimental results.