Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses various methods for processing and separating human skin samples for research purposes, evaluating factors like processing time and cell viability, but reports no new experimental findings.

This study concluded that, in male patients with mild-to-moderate androgenetic alopecia, injections of PRP prepared by an automated method combined with topical 5% minoxidil were effective and safe, showing superior clinical efficacy and patient satisfaction compared to PRP alone.

This study identified histologic lesions and a defect in adhesion molecules causing hair loss in mice with the bal mutation, linked to a mutation in the desmoglein 3 gene.

In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.

The researchers reported that yak hair fibers undergo macromolecular conformational changes and partial slippage of macromolecules during stretching, confirming this as the main stretching mechanism when the stretching ratio is large.

This study found that follicular acantholysis is a common histopathological feature in pemphigus, with differences in depth between pemphigus vulgaris and pemphigus foliaceus lesions that may aid in diagnosis.

This article discusses the therapeutic use of platelet-rich plasma (PRP) in dermatology, specifically its challenges and potential in treating conditions like lichen planopilaris, but reports no new findings.

This study found that loss of integrin-β4 or its ligand, laminin-α3β3ɣ2, in keratinocytes increases differentiation via delamination, and demonstrated a role for hemidesmosomes in epidermal differentiation through both mitotic and non-mitotic mechanisms, influenced by Notch signaling.

This study systematically reviews the development and applications of drug-loaded nanofiber scaffolds in wound healing, highlighting challenges such as maintaining drug activity and achieving controlled release, while summarizing preparation methods and describing advanced drug delivery schemes.

This study established a protocol using anti-steroid antibodies to differentially label epidermal cell contributors, suggesting potential applications in simplifying complex trace DNA mixtures before profiling.

In this study, knockout of B-raf and C-raf genes in mice showed they are not needed for early melanocyte development, but are crucial for maintaining melanocyte stem cells, as evidenced by hair graying due to stem cell depletion.

Glycogen helps E. coli cells divide unevenly and organize their contents.

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

This review discusses regenerative skin wound healing in mammals, focusing on growth factor- and stem cell-based treatments, but reports no new research results.

In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.

This study found that 3D cultured hair follicle-like constructs, which include keratinocytes and dermal papilla cells, showed improved gene expression and cell interactions relevant to hair follicle development.

This study proposes a two-step method that may enhance the generation of stem-like epidermal cells with superior proliferation and differentiation potential for skin regeneration.

This paper describes a protocol for isolating and culturing skin-derived precursors to potentially induce hair growth and regenerate hair follicles, but reports no new experimental findings.

This narrative review discusses the discovery of plasticity in epidermal stem cells using single-cell transcriptomics, but reports no new results; it highlights the potential implications for regenerative medicine.

This study describes a method to isolate and analyze young and mature type VI trichomes from wild tomato species using autofluorescence-based cell sorting.

This study found that donor age and culture medium significantly impact the quality of human full-thickness skin models, with implications for their use as animal model alternatives in research.

This study describes a method for isolating stem cells and keratinocytes from mouse hair follicles using FACS technology, facilitating the study of stem cell biology.

This study developed microfluidic-assisted GelMA-MSC/HAD-EPC microspheres that efficiently generated hair follicles in nude mice, suggesting a promising strategy for advancing hair-regenerative medicine.

This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.

This article reviews in vitro methods for evaluating whitening, anti-wrinkle, and hair growth ingredients in cosmetics, noting that more human-relevant evaluation methods with reliable biomarkers are needed; it presents no new clinical outcomes.

This study found that in a rat skin model, fat cells inhibited the proliferation of organoid hair follicle cells and fibroblasts but may have accelerated hair follicle cell differentiation.

This study describes a method for labeling and tracking hair follicle stem cells in mouse skin using a Cre/lox recombination system with tamoxifen, providing insights into stem cell behavior and contribution to tissue regeneration.

This study found that lentiviral vector tropism in three-dimensional skin tissue is distinct from keratinocytes in culture and is influenced by complex extracellular interactions.

This study concluded that high-purity rat hair follicle stem cells with strong proliferation abilities can be obtained using a modified culture and purification method.

This study achieved a first by successfully forming large quantities of dermal papilla spheroidal microtissues, which retained their hair induction potential, using a micropatterned culture system.