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GlossaryCell Proliferation Marker

substance indicating cell division and growth rates

A Cell Proliferation Marker is a substance or molecule used to detect and measure the rate at which cells are dividing and growing. These markers are crucial in both research and clinical settings to understand cell growth patterns, especially in contexts like cancer research, tissue regeneration, and hair growth studies. Common examples include Ki-67 and BrdU, which are often used to identify actively dividing cells.

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Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia

research Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia

13 citations, September 2020 in “International Journal of Molecular Sciences”

PRP therapy and minoxidil combo works best for male hair loss.

research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene

January 2024 in “Animals”

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

research Costunolide Promotes the Proliferation of Human Hair Follicle Dermal Papilla Cells and Induces Hair Growth in C57BL/6 Mice

21 citations, May 2018 in “Journal of Cosmetic Dermatology”

Costunolide helps human hair cells grow and can stimulate hair growth in mice.

research Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells

13 citations, September 2021 in “Current Issues in Molecular Biology”

Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.

research Transforming Growth Factor-Alpha Immunoreactivity During Induced Hair Follicle Growth Cycles in Sheep and Ferrets

6 citations, April 1996 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

research The Effect of EGR1 on the Proliferation of Dermal Papilla Cells

5 citations, July 2022 in “Genes”

Increasing EGR1 levels makes hair root cells grow faster.

research Macrophage-Derived Extracellular Vesicle Promotes Hair Growth

51 citations, April 2020 in “Cells”

Special cell particles from macrophages can help hair grow.

research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway

25 citations, September 2020 in “Molecules”

Quercitrin may help treat hair loss by promoting hair growth and improving cell health.

Combination of an Engineered Lactococcus Lactis Expressing CXCL12 with Light-Emitting Diode Yellow Light as a Treatment for Scalded Skin in Mice

research Combination of an Engineered Lactococcus Lactis Expressing CXCL12 with Light-Emitting Diode Yellow Light as a Treatment for Scalded Skin in Mice

6 citations, July 2021 in “Microbial biotechnology”

The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.

research Ganoderma Lucidum Extract Attenuates Corticotropin-Releasing Hormone Induced Cellular Senescence in Human Hair Follicle Cells

April 2024 in “iScience”

Ganoderma lucidum extract may help treat stress-related hair loss.

research Faculty Opinions Recommendation of The Effect of Autologous Activated Platelet-Rich Plasma (AA-PRP) Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

July 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

AA-PRP injections significantly promote hair growth but need better study design for clear efficacy.

research Differential Effects of Wnt5a on the Proliferation, Differentiation, and Inflammatory Response of Keratinocytes

6 citations, December 2017 in “Molecular Medicine Reports”

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

research Dihydroartemisinin Attenuates Benign Prostatic Hyperplasia in Rats by Inhibiting Prostatic Epithelial Cell Proliferation

4 citations, August 2021 in “Annals of Translational Medicine”

Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.

research Exosomes Derived From Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation Through The Wnt3a/Beta-Catenin Signaling Pathway

2 citations, November 2022 in “Oxidative Medicine and Cellular Longevity”

Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.

RSPO1-Mutated Keratinocytes From Palmoplantar Keratoderma Display Impaired Differentiation and Invasiveness: Implications for Squamous Cell Carcinoma Susceptibility in Patients With 46XX Disorder of Sexual Development

research RSPO1-Mutated Keratinocytes From Palmoplantar Keratoderma Display Impaired Differentiation and Invasiveness: Implications for Squamous Cell Carcinoma Susceptibility in Patients With 46XX Disorder of Sexual Development

5 citations, July 2022 in “Orphanet journal of rare diseases”

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

research The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

3 citations, February 2022 in “Frontiers in cell and developmental biology”

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Urotensin II Promotes the Proliferation and Secretion of Vascular Endothelial Growth Factor in Rat Dermal Papilla Cells by Activating the Wnt-Beta-Catenin Signaling Pathway

research Urotensin II Promotes the Proliferation and Secretion of Vascular Endothelial Growth Factor in Rat Dermal Papilla Cells by Activating the Wnt-Beta-Catenin Signaling Pathway

June 2023 in “Italian Journal of Medicine”

Urotensin II increases growth and VEGF production in rat skin cells by turning on the Wnt-β-catenin pathway.

research Biomimetic Scaffolds: A Novel Approach to Three-Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

1 citations, March 2024 in “Nanomaterials”

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

research Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs

12 citations, November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

Laminin 332 is essential for normal skin cell behavior and structure.

Hair Follicle Changes Following Intense Pulsed Light Axillary Hair Reduction: Histometrical, Histological, and Immunohistochemical Evaluation

research Hair Follicle Changes Following Intense Pulsed Light Axillary Hair Reduction: Histometrical, Histological, and Immunohistochemical Evaluation

8 citations, February 2017 in “Archives of Dermatological Research”

Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.

Study on the Mechanism of Cadmium Chloride Pollution Accelerating Skin Tissue Metabolism Disorder, Aging and Inhibiting Hair Regeneration

research Study on the Mechanism of Cadmium Chloride Pollution Accelerating Skin Tissue Metabolism Disorder, Aging and Inhibiting Hair Regeneration

4 citations, October 2022 in “Frontiers in public health”

Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.

research Acute Sensitivity of the Oral Mucosa to Oncogenic K-ras

12 citations, March 2011 in “Journal of pathology”

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

research Role of the Wnt Signaling Pathway in Keratoacanthoma

2 citations, November 2019 in “Cancer reports”

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

research Suppression of Wnt/β-Catenin Signaling by EGF Receptor Is Required for Hair Follicle Development

25 citations, September 2018 in “Molecular Biology of the Cell”

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

research Dormancy in the Stem Cell Niche

29 citations, March 2012 in “Stem Cell Research & Therapy”

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

Histopathological Findings and Proliferative Activity of Canine Sebaceous Gland Tumors with a Predominant Reserve Cell Population

research Histopathological Findings and Proliferative Activity of Canine Sebaceous Gland Tumors with a Predominant Reserve Cell Population

5 citations, February 2015 in “Journal of Comparative Pathology”

High proliferative activity and peripheral invasion indicate malignancy in canine sebaceous gland tumors; the term 'epithelioma' should be updated for clarity.