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    Glossary Cell Density

    number of cells in a specific volume or area

    Cell density refers to the number of cells present in a given volume or area of a tissue or culture. In the context of hair and alopecia, understanding cell density can help researchers determine the health and growth potential of hair follicles, as higher cell density in hair follicles might indicate robust hair growth, while lower cell density could be associated with thinning hair or hair loss.

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    1. Proliferation and Differentiation of Cultured Human Keratinocytes is Modulated by 1,25(OH)<sub>2</sub>D<sub>3</sub> and Synthetic Vitamin D<sub>3</sub> Analogues in a Cell Density‐, Calcium‐ and Serum‐Dependent Manner* Pharmacology & toxicology · 1997 · 39 citations
    2. Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair International Journal of Molecular Sciences · 2015 · 10 citations
    3. The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study. Aesthetic Surgery Journal · 2021 · 6 citations
    4. 653 Substance P ameliorates epidermal thickness, basal cell density, and asymmetric stem cell self-renewal in skin with decreased sensory innervation Journal of Investigative Dermatology · 2024
    5. Control of myeloid cell density in barrier tissues FEBS Journal · 2020 · 11 citations
    6. Commentary on: The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) in Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB Study Aesthetic Surgery Journal · 2021
    7. Feather arrays are patterned by interacting signalling and cell density waves PLoS Biology · 2019 · 133 citations
    8. ISID1373 - Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata 2023
    9. 1373 Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata Journal of Investigative Dermatology · 2023
    10. Changes in intraepidermal nerve fiber and Langerhans cell densities in the plantar skin of rats after mercuric chloride exposure Journal of the Peripheral Nervous System · 2017 · 6 citations
    11. Correction to: The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study Aesthetic Surgery Journal · 2022 · 1 citations
    12. Signaling in the stem cell niche: regulating cell fate, function and plasticity Development · 2018 · 139 citations
    13. Photobiomodulation of human dermal fibroblasts in vitro: decisive role of cell culture conditions and treatment protocols on experimental outcome Scientific Reports · 2017 · 39 citations
    14. Cell and Tissue Damage after Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects after a Single and Fractional Doses Cells Tissues Organs · 2014 · 14 citations
    15. Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models BioMed Research International · 2014 · 4 citations
    16. Adipose derived stem cell based therapies or male/female pattern hair loss Journal of stem cell research and medicine · 2016 · 1 citations
    17. Adipose derived stem cell based therapies or male/female pattern hair loss Journal of stem cell research and medicine · 2016 · 1 citations
    18. Three-Dimensional Analysis of Cell Division Orientation in Epidermal Basal Layer Using Intravital Two-Photon Microscopy PLoS ONE · 2016 · 31 citations
    19. Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs Journal of Cosmetic Dermatology · 2015 · 36 citations
    20. Autologous cell–based therapy for male and female pattern hair loss using dermal sheath cup cells: A randomized placebo-controlled double-blinded dose-finding clinical study Journal of The American Academy of Dermatology · 2020 · 22 citations
    21. Efficacy assessment of mesenchymal stem cell transplantation for burn wounds in animals: a systematic review Stem Cell Research & Therapy · 2020 · 21 citations
    22. The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization and Hair Growth in a Porcine Model PLoS ONE · 2016 · 16 citations
    23. Progenitor‐cell‐enriched micrografts as a novel option for the management of androgenetic alopecia Journal of Cellular Physiology · 2019 · 14 citations
    24. The efficacy of adipose stem cell‐derived exosomes in hair regeneration based on a preclinical and clinical study International Journal of Dermatology · 2024 · 2 citations
    25. Stem cell–derived conditioned medium for alopecia: A systematic review and meta-analysis Journal of plastic, reconstructive & aesthetic surgery · 2023 · 1 citations
    26. Tendon dECM Composited with Chitosan with Loading Skin Precursor Stem Cell Exosome for Enhanced Diabetic Wound Healing Gels · 2026
    27. COMPARATIVE EFFECTIVENESS OF REGENERATIVE BIOLOGICS IN AESTHETIC DERMATOLOGY: A SYSTEMATIC REVIEW WITH QUANTITATIVE SYNTHESIS EVALUATING EXOSOMES, PRP AND STEM-CELL-DERIVED THERAPIES ON SKIN AND HAIR Zenodo (CERN European Organization for Nuclear Research) · 2026
    28. COMPARATIVE EFFECTIVENESS OF REGENERATIVE BIOLOGICS IN AESTHETIC DERMATOLOGY: A SYSTEMATIC REVIEW WITH QUANTITATIVE SYNTHESIS EVALUATING EXOSOMES, PRP AND STEM-CELL-DERIVED THERAPIES ON SKIN AND HAIR Zenodo (CERN European Organization for Nuclear Research) · 2026
    29. Optimizing hair transplant outcomes: integration of AI, robotics, and stem cell therapies International Journal of Zoology and Applied Biosciences · 2025
    30. Uncontrolled Clinical Trial of Quality- and Quantity-cultured Peripheral Blood Mononuclear Cell Treatment for Androgenic Alopecia Plastic & Reconstructive Surgery · 2025