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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Special fiber materials boost the healing properties of certain stem cells.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Wnt ligands are crucial for hair growth and repair.

Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Current treatments for alopecia show no significant long-term benefits.

Low iron levels may be linked to some types of hair loss in women.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Telocytes might help with skin repair and regeneration.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Estrogen therapy can reduce skin aging but has cancer risks.