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    Did you mean CD8+ T cells?
    Glossary CD8+ T cells

    specialized immune cells that destroy infected or cancerous cells

    CD8+ T cells, also known as cytotoxic T cells or killer T cells, are a type of white blood cell that plays a crucial role in the immune system. They are responsible for identifying and destroying infected or cancerous cells by recognizing specific antigens presented on the surface of these cells.

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    Research 30 of 1000+

    1. High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata JCI insight · 2018 · 46 citations
    2. A mouse model of vitiligo based on endogenous auto-reactive CD8 + T cell targeting skin melanocyte Cell Regeneration · 2022 · 24 citations
    3. Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level Indian Journal of Dermatology, Venereology and Leprology · 2012 · 24 citations
    4. SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cell-mediated autoimmune destruction Oncotarget · 2017 · 16 citations
    5. Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases International journal of molecular sciences · 2023 · 6 citations
    6. Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease Cell Reports · 2025 · 4 citations
    7. Effective Role of Cytotoxic CD8+ T Cell in Iraqi Alopecia areata Patients Medical Journal of Babylon · 2024 · 2 citations
    8. High throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in Alopecia Areata immuneACCESS · 2018 · 1 citations
    9. CD8 T cells require IFNg to induce disease in a murine model of Alopecia Areata 2310132 The Journal of Immunology · 2026
    10. 042 Characterization of Pathogenic CD8+ T Cells in an adoptive transfer Mouse Model of Alopecia Areata in C3H/HeJ mice Journal of Investigative Dermatology · 2025
    11. The function of BST2 in γδ T Cells, CD8 T Cells, and macrophages in alopecia areata pathogenesis 4231 The Journal of Immunology · 2025
    12. Epidermal γδ T cells, CD8 T cells and macrophages are increased in number in alopecia areata and express BST2 as part of an interferon-driven antiviral gene signature bioRxiv (Cold Spring Harbor Laboratory) · 2025
    13. Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia Journal of Inflammation Research · 2025
    14. 057 Single cell RNA and TCR sequencing reveals hyperexpansion of T cell clones and novel regulatory mechanisms of CD8+ T cells in murine alopcecia areata skin and draining lymph nodes Journal of Investigative Dermatology · 2024
    15. 039 Expansion of regulatory T Cells restrains pathogenic CD8 T Cells in a murine model of alopecia areata Journal of Investigative Dermatology · 2024
    16. 452 Braicitinib treatment reduced the expansion of CD8+ T cells in C3H mice with skin grafts-induced alopecia areata Regular and Young Investigator Award Abstracts · 2023
    17. Generation of autoreactive CD8 T cell in a mouse model of alopecia areata The Journal of Immunology · 2023
    18. ISID1373 - Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata 2023
    19. 1373 Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata Journal of Investigative Dermatology · 2023
    20. PD59-09 PHOSPHODIESTERASE INHIBITORS COULD REVERSE THE PROLIFERATION OF BPH EPITHELIAL CELLS INDUCED BY CD8+ T CELLS IN LOW ANDROGEN CONDITION The Journal of Urology · 2018
    21. PD23-01 INHIBITOR OF 5A-REDUCTASE TYPES II PROMOTES THE INFILTRATION OF CD8+T CELLS IN BPH TISSUES. The Journal of Urology · 2014
    22. Pathogenic CD8+ T cells target K71+ Henle’s layer by forming cytolytic immune synapses in Alopecia Areata Research Square · 2026
    23. 068 Pathogenic Th17 cells, CD8+CD69+CD49a- tissue-resident memory T cells and common γ chain receptor + natural killer cells express more IL-17, compared to IFN-γ, under the foxp3+ memory regulatory T cells-depleted microenvironment in patients with chronic alopecia areata Journal of Investigative Dermatology · 2023
    24. 060 Heterogeneity and lineage development of memory CD8+ T cells after viral infection of skin Journal of Investigative Dermatology · 2022
    25. Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation Nature communications · 2016 · 155 citations
    26. CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata Journal of Immunology · 2016 · 64 citations
    27. Antroquinonol Exerts Immunosuppressive Effect on CD8<sup>+</sup> T Cell Proliferation and Activation to Resist Depigmentation Induced by H<sub>2</sub>O<sub>2</sub> Oxidative medicine and cellular longevity · 2017 · 11 citations
    28. T-cell “induced-self” MHC class I/peptide complexes may enable “de novo” tolerance induction to neo-antigens occurring outside of the thymus Experimental dermatology · 2016 · 8 citations
    29. CD80CD86 deficiency disrupts regulatory CD4+FoxP3+T cell homoeostasis and induces autoimmune-like alopecia Experimental dermatology · 2017 · 6 citations
    30. Alopecia areata possibly induced by autoimmune reaction in a patient with human T‐cell lymphotropic virus‐1‐associated myelopathy The Journal of Dermatology · 2013 · 6 citations