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CCCA affects Black men too, with a genetic link found in the PADI3 gene.

This study describes the diagnosis and successful management of Cronkhite-Canada syndrome in a 78-year-old man, highlighting improvement in symptoms and endoscopic findings after treatment with prednisone and supportive therapies.

In this study, researchers analyzed skin tumors from patients with CYLD cutaneous syndrome and found that loss of CYLD function is linked to changes in cellular signaling pathways, particularly NF-κB signaling, and leads to increased secretion of specific extracellular matrix proteins.

More research is needed on CCCA in children, especially Black and Asian adolescents.

This study identified shared gene expression changes and immune cell infiltration patterns that may contribute to hair loss in alopecia areata and cutaneous lupus erythematosus, but also highlighted factors that might preserve hair in psoriasis patients.

In this study, the authors identified and characterized the Get3d protein, conserved across plants and photosynthetic bacteria, which localizes to the chloroplast in Arabidopsis thaliana and potentially plays a role in tail-anchored protein targeting, linked to photosynthesis homeostasis.

In this study, a mouse model of scarring alopecia demonstrated significantly reduced CD200R expression in affected skin, which may contribute to immune attacks on hair follicles.

This study reports that CD200R expression is significantly reduced in an experimental mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.

This study in Kitui County, Kenya, identified histopathological lesions due to Cordylobia anthropophaga infestations in dogs, including parasitic granulomas and eosinophilic lymphadenitis, leading to severe health effects such as emaciation and potential death.

Certain immune cells help hair growth by regulating iron in the skin.

This report describes a case of Cronkhite-Canada syndrome diagnosed in a 54-year-old man with symptoms including gastrointestinal polyps, alopecia, skin hyperpigmentation, and severe diarrhea, who experienced significant symptom improvement with azathioprine.

The authors maintain there is a significant link between vitamin D deficiency and central centrifugal cicatricial alopecia in Black patients, and call for more research on the topic.

This study reported that an HS-associated NCSTN mutation in iPSC-derived skin organoids led to altered hair follicle stem cell differentiation and increased expression of proteins linked to HS inflammation.

This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.

This study found that the immunological characterization of ichthyoses as psoriasiform or atopic patterns could help improve treatment, highlighting the need for targeted therapies to address itch and skin inflammation.

This article explores potential risk factors for central centrifugal cicatricial alopecia and suggests that seborrheic dermatitis may play a role in its development, but it reports no new scientific findings.

This review discusses the classification of lichen planopilaris and its subtypes under the proposed term "lichenoid alopecias," suggesting they exist along a clinical and histological spectrum.

This study suggests that distinct alopecia scoring systems measure percent hair loss as a common underlying feature, with strong correlations observed between different types of hair loss assessments.

This article discusses the clinical features and treatment options for common types of hair loss in women and reports no new clinical results.

This descriptive study reported that Chronic Cutaneous Lupus Erythematosus was the most prevalent subtype, highlighting distinct clinical and pathological features among Cutaneous Lupus Erythematosus subtypes.

This study observed that photobiomodulation therapy may contribute to hair growth stability or improvement in individuals with darker skin types, without reported adverse events, though its findings are limited by a small sample size.

This report presents two cases of systemic lupus in male patients with a distinct form of alopecia that combines both scarring and non-scarring elements, highlighting the variability in lupus-related hair loss presentations.

This chapter reviews skin manifestations in common rheumatic diseases, particularly those with polyarthritis, and offers a differential diagnosis of erythema nodosum without presenting new research findings.

In this study, 25% of CCHCR1-deficient mice exposed to stress developed hair loss similar to human alopecia areata, suggesting CCHCR1 is a susceptibility gene for the disease.

This study found that fibrosis-associated trochanters in central centrifugal cicatricial alopecia are enriched with hair follicle stem cells and may indicate a disrupted stem cell niche contributing to scarring.

In this study, researchers identified IL18R+ thymus-resident regulatory T cells in mice, demonstrating their unique molecular features and resistance to age- and stress-induced thymus involution, highlighting IL18 signaling's role in Treg migration and retention.

This report documents a case of Cronkhite-Canada Syndrome in a 56-year-old Laotian man, who successfully improved with vitamin supplementation and medical treatment after experiencing weight loss, alopecia, and gastrointestinal polyposis.

This study found that mutations in the PADI3 gene, which is important for hair shaft formation, may contribute to central centrifugal cicatricial alopecia among patients.

CCCA in women of African ancestry may be caused by PADI3 gene mutations and intense hair grooming.

This article reviews the characteristics of Lupus Erythematosus Panniculitis as a rare variant of Chronic Cutaneous Lupus Erythematosus, with no new clinical results reported.