Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

A thorough assessment and combined treatment are crucial for managing complex alopecia, especially in patients with skin of color.

This study found that patients with central centrifugal cicatricial alopecia were less likely to report treatment improvement and more commonly associated with certain hairstyling practices compared to those with other scarring alopecias.

In this retrospective cohort study, researchers found that exposure to 5-alpha reductase inhibitors and spironolactone in female alopecia patients was not linked to an increased risk of developing malignant or benign gynecologic tumors when compared to minoxidil use.

In this retrospective chart review, researchers found that patients with scarring alopecia, including central centrifugal cicatricial alopecia, have a higher prevalence of various systemic comorbidities, such as vitamin D deficiency and metabolic syndrome, compared to the general US population.

This research highlights the potential of non-coding RNAs as biomarkers and therapeutic targets in dermatology, while experimental studies on a unique GVM case suggest CCM2L may modulate disease severity, advancing understanding of genetic mechanisms in rare skin disorders.

This study found that patients with central centrifugal cicatricial alopecia preferred shared decision-making with their doctors regarding treatment management.

Genetic changes in specific proteins contribute to hair loss in some women of African descent.

This study introduced the C-CAT, a new assessment tool for central centrifugal cicatricial alopecia, and found that established treatments improved symptoms in most patients over six months.

In this case series, low-dose oral metformin was associated with improvements in symptoms and gene expression changes in Black female patients with treatment-resistant central centrifugal cicatricial alopecia, suggesting a potential therapeutic role for metformin in managing this condition.

In this case study, researchers detailed two Saudi cases of the ultra-rare Trichohepatoneurodevelopmental syndrome, identifying pathogenic variants in the CCDC47 gene and reinforcing a strong gene-disease association, which helps clarify the disorder's clinical features and genetic mutations.

This study found that in mice with alopecia areata, CD8+ T cells showed clonal expansion and specific regulatory networks, which might help identify new therapeutic targets for patients not responding to JAK inhibitors.

OR101 may effectively treat atopic dermatitis and similar skin conditions.

In this article, a case report examines the use of topical metformin 10% cream for treating central centrifugal cicatricial alopecia, contributing to existing literature on potential treatments for this condition.

This abstract provides information on potential conflicts of interest and acknowledges sources of support for the findings, but does not report specific study results.

Men with CCCA often face delayed diagnosis and severe hair loss, highlighting the need for earlier recognition and treatment.

The researchers reported increased ubiquitination of proteins such as the insulin receptor in CYLD cutaneous syndrome skin tumors, suggesting that CYLD dysfunction may affect protein secretion and signaling processes.

Diagnosing and treating CCCA requires understanding multiple causes and using various diagnostic tools.

In this pilot study, participants with lymphocytic primary cicatricial alopecia who applied 6% topical gabapentin solution twice daily for 12 weeks experienced significant symptom reduction, though there was no noticeable change in nerve fibre density or neuropeptide expression.

In this case report, a 42-year-old male diagnosed with Cronkhite-Canada syndrome presented symptoms like chronic diarrhea, significant weight loss, skin hyperpigmentation, alopecia, and nail dystrophy, with endoscopic findings revealing numerous gastrointestinal polyps.

This study reported that a newly developed hydrogel patch, designed to recruit regulatory T cells through ROS-triggered release of CCL22, improved wound healing and hair follicle regeneration in a diabetic mouse model by scavenging ROS, thereby protecting Tregs and suppressing Th17 cells.

This report highlights that scientific collaborations have led to a rise in publications focused on African skin and hair, which could inform the development of locally tailored products and awareness campaigns.

More research is needed to understand sex and racial differences in long COVID.

Biopsies matched initial diagnoses in 76.6% of black women with alopecia and led to treatment changes in 44% of cases.

This case report describes a 68-year-old woman diagnosed with chronic cutaneous lupus, characterized by irregular plaques with distinct pigmentation and scarring alopecia, confirmed through histopathology revealing specific skin changes.

This study emphasizes the importance of dermatologists practicing cultural sensitivity and providing appropriate recommendations for Black women experiencing hair loss, as understanding textured hair can present diagnostic challenges.

In this study, CCCA patients were found to have higher odds of metabolic, autoimmune, atopic, and psychiatric comorbidities compared to matched controls.

In this study using Angora rabbits, researchers found that the FRZB gene inhibits hair follicle development by modulating the Wnt/β-catenin signaling pathway, affecting the expression of various genes related to this pathway and altering cell proliferation and apoptosis.

This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.

This study found no significant difference in comorbidities between patients with central centrifugal cicatricial alopecia and those with nonscarring alopecia.

In this study, a case of a 70-year-old woman with central centrifugal cicatricial alopecia showed that using a high-quality hair prosthesis improved her quality of life and mood, as measured by PHQ-9 and Skindex-29 scores, though such wigs are rarely covered by insurance.