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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Wheat straw is valuable for its health benefits and various industrial uses.

The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.

Platycarya strobilacea extract is a strong antioxidant that can grow hair better than minoxidil.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Hibiscus petals improved blood sugar and stress responses in diabetic rats.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

Natural compounds, especially Withaferin-A, may help treat post-COVID-19 complications, but some may have side effects.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

Proper care and diet are crucial to prevent health issues in gerbils.