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Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies

research Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies

253 citations, March 2006 in “The Journal of Clinical Endocrinology and Metabolism”

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ

218 citations, October 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

research Particulate Matter 2.5 Damages Skin Cells by Inducing Oxidative Stress, Subcellular Organelle Dysfunction, and Apoptosis

215 citations, March 2018 in “Archives of Toxicology”

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

research The Prevalence of Polycystic Ovary Syndrome in a Community Sample of Iranian Population: Iranian PCOS Prevalence Study

215 citations, January 2011 in “Reproductive Biology and Endocrinology”

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

research Polycystic Ovarian Syndrome: Correlation Between Hyperandrogenism, Insulin Resistance, and Obesity

195 citations, November 2019 in “Clinica Chimica Acta”

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.