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Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Testosterone may slow down wound healing and increase inflammation.

Pannexin 3 is important for bone formation and the development of bone cells.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

Stress hormone CRF can cause hair loss by affecting hair growth cells and hormones.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

Skin problems are common in thyroid disorders, with dry skin in hypothyroidism and warm, soft skin in hyperthyroidism.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Arachidonic acid helps hair grow by increasing growth factors and improving follicle health.