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Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

ILK is essential for proper hair follicle development and structure.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

Key genes linked to hair growth and cancer were identified in hairless mice.

Chicken egg yolk peptides can promote hair growth by increasing a specific growth factor.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Targeting NETs may help reduce fibrosis in Crohn's disease.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.