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Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.

Not getting enough minerals can lead to health problems and shorter lifespans.

Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.

Vitamin D is crucial for bone health and preventing serious diseases.

VDR regulation varies by tissue and is crucial for its biological functions.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Vitamin D receptor is crucial for starting hair growth after birth.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Four-amino acid part makes enzyme sensitive to finasteride.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.