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Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

The hair cuticle is made of tough proteins that protect the hair, but more research is needed to fully understand its structure.

Vitamin D is crucial for bone health and preventing serious diseases.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

PRP is effective for treating hair loss, especially with other treatments.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Paclitaxel is an effective cancer drug with side effects and potential new uses beyond cancer.

Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.

The BUZZ gene is important for root hair growth and overall root structure in the plant Brachypodium distachyon.

More research is needed to understand how testosterone is maintained in adult males.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

Melatonin helps regulate sleep and may aid in treating various health issues.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

Dlx3 is essential for hair growth and regeneration.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Nanotechnology shows promise for better chronic wound healing but needs more research.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.

Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Probiotics show promise for health benefits but need more research to understand how they work.

New therapies are being developed that target integrin pathways to treat various diseases.