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This review describes the toxicities associated with calcineurin inhibitors, used in kidney transplantation, which include nephrotoxicity, cardiovascular and endocrine issues, and quality of life impacts, without reporting new clinical results.

This study found that cyclosporin A treatment enhances hair growth in mice by inhibiting calcineurin-NFAT1 activity, which alters keratinocyte differentiation and apoptosis-related gene expression in hair follicles.

This case report describes a 7-year-old boy with alopecia areata and reduced vitamin D receptor expression whose condition improved after using calcipotriol, a strong vitamin D analog.

This study observed that calcifying epithelioma of Malherbe is composed of tumor cells that differentiate into both hair cortex and outer root sheath, supporting its hair follicle origin.

The researchers reported that in mice, prolactin signaling in the skin epithelium inhibits hair follicle stem cell activation, promoting quiescence during periods of high serum prolactin like pregnancy and lactation.

This study found that topical calcipotriol may safely and effectively treat mild-to-moderate patchy alopecia areata, with significant hair regrowth observed in the majority of participants over 12 weeks.

This study found that the diphosphonate ethan-1-hydroxy-1,1-diphosphonat was the most effective compound in preventing calcifications in rats induced by DHT, compared to other phosphatase inhibitors and polyphosphates tested.

This article highlights the benefits of combining calcipotriene and betamethasone for treating localized plaque-type, scalp, and nail psoriasis, enhancing effectiveness while reducing side effects compared to single-agent therapies.

This case report describes a 9-year-old Korean boy with a calcified nodule on his earlobe, confirmed by histopathologic examination and Von Kossa staining.

This study found that microneedling combined with calcipotriol plus betamethasone was more effective in treating vitiligo than microneedling with tacrolimus, particularly in difficult-to-treat areas.

This study reported that topical calcipotriol did not reduce hypertrophic scar formation in women post reduction mammoplasty, but found a strong association between activated keratinocytes and scar formation.

This study reported successful treatment of peeling skin syndrome using topical calcipotriol.

This study found that calcipotriol scalp solution was more effective than a coal tar-based shampoo for treating mild to moderate scalp psoriasis and showed continued efficacy with long-term use.

This case study highlights a pediatric instance of eruptive vellus hair cysts partially responding to calcipotriene cream, aiming to remind clinicians about this often overlooked condition.

This study reports that a German Shepherd developed generalized calcinosis cutis following a presumed bacterial infection, representing the first known case linked to such an infection in adult dogs.

This case report describes a 5-year-old boy with extensive epidermal nevus who experienced marked improvement using a topical calcipotriol/betamethasone dipropionate combination ointment.

This study found that experimentally induced calcification in rat skin led to rapid and localized mineralization in hair follicles, progressing to more extensive calcification with prior hypercalcemic treatment.

In this study of 35 patients with scalp alopecia areata, calcipotriol ointment led to faster and greater hair regrowth than clobetasol, though differences were not statistically significant.

The researchers reported that the antipsoriatic compounds 1,25-dihydroxy-vitamin D3 and calcipotriol thinned the living cell compartment in organotypic ORS cultures by accelerating the differentiation pathway rather than affecting proliferation.

In this article, the authors reported that calcipotriol/betamethasone dipropionate aerosol foam significantly improved scalp psoriasis symptoms in three patients by reducing itching and improving flaky patches within a four-week treatment period, confirming its efficacy and enhanced skin penetration compared to older formulations.

In this study, combining topical calcipotriol with mometasone results in greater improvement in alopecia areata treatment compared to using mometasone alone, as evidenced by a more significant reduction in SALT score over 24 weeks.

This study reports a rare case of a 40-year-old woman with multiple calcified trichilemmal cysts, associated with alopecia universalis and suggesting a potential genetic link.

This study found that localized skin calcification could be induced in adult rats through dihydrotachysterol treatment combined with topical trauma, offering an experimental model for calcifying scleroderma.

In this study, the growth-inhibiting potential of calcipotriol did not affect the telogen/anagen hair ratio during treatment for scalp psoriasis.

The authors concluded that incorporating routine endocrinology consultations into transplant care could address CNI-related endocrine toxicities, but prospective studies are needed to assess the impact on graft and patient survival.

This study found that combining follicular unit extraction with topical calcipotriol betamethasone dipropionate showed the best repigmentation results in treating stable nonsegmental vitiligo.

This review discusses treatment strategies for alopecia areata, emphasizing current immunomodulation approaches but reports no new clinical results.

This study found that epithelial components of calcifying epithelioma of Malherbe showed lectin binding and keratin staining patterns similar to normal hair follicles, with prominent Con A staining in tumor giant cells.

In this case report, a 15-year-old golden retriever with calcinosis cutis showed accelerated improvement in FLE-treated skin infections compared to untreated areas, highlighting FLE's potential as a treatment adjunct.

This study reviewed the genetic and phenotypic aspects of Olmsted syndrome, highlighting pathogenic mutations in TRPV3 and MBTPS2 genes and their association with specific skin manifestations like symmetrical keratoderma and hyperkeratotic plaques.