March 2008 in “European Urology Supplements” Finasteride and dutasteride can affect sexual function in BPH patients.
January 2008 in “Journal of Beijing Normal University” This study found that terazosin hydrochloride, when used with finasteride, improved prostate volume and lowered blood pressure in BPH patients with high blood pressure, although the overall treatment effect was not significantly different from controls.
April 2006 in “The Journal of Urology” This study investigates the potential influence of genetic variations in the 5α-reductase type 2 gene on the effectiveness of finasteride treatment for benign prostatic hyperplasia, but it reports no new clinical results.
April 2004 in “Journal watch” Finasteride effectively reduces the need for surgery and urinary issues in men with BPH over the long term.
January 2004 in “Anticancer Research” This study suggested that long-term finasteride treatment for BPH patients may induce neuroendocrine activity in the prostate, potentially increasing the risk of developing aggressive prostate cancer.
January 2004 in “Zhongguo yiyuan yongyao pingjia yu fenxi” This study found that combining tamsulosin with finasteride was the most cost-effective treatment for mild to moderate BPH among the regimens tested.
February 2003 in “European Urology Supplements” Baseline PSA levels affect general health and sexual satisfaction in men with BPH treated with finasteride or placebo.
March 2016 in “European Urology Supplements” This study identified that methylation of the 5-AR2 gene promoter is linked to reduced expression of 5-AR2 protein, which may explain why some BPH patients are resistant to finasteride treatment.
November 2022 in “Journal of the Endocrine Society” This study observed improvements in hair loss, acne, and BPH symptoms after addressing vitamin D and progesterone deficiencies in male patients, suggesting the potential benefits of this therapeutic approach.
September 2022 in “PubMed” Entadfi, a mix of finasteride and tadalafil, is used for BPH.
July 2020 in “European urology open science” Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.
January 2018 in “International Journal of Medical Research and Health Sciences” This study found that prescribing finasteride for two weeks before TURP surgery reduces intraoperative and postoperative blood loss, the rate of blood transfusion, and irrigation fluid usage in patients with BPH.
20 citations
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December 2013 in “Journal of Dermatology” This study found that UV-B exposure significantly increased the expression of inflammatory cytokines IL-1β and IL-8 in cultured sebocytes.
5 citations
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January 2013 in “Cells Tissues Organs” This study found that activin B promotes the initiation and development of hair follicles in both cultured and neonatal mouse skin models.
11 citations
,
January 1995 in “Biomedicine & pharmacotherapy” This review discusses the use of finasteride and alpha antagonists for symptomatic benign prostatic hypertrophy and suggests current studies are evaluating combination therapies as potential non-surgical alternatives.
8 citations
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August 2021 in “Aging” This animal study found that berberine may alleviate benign prostatic hyperplasia by reducing inflammation and oxidative stress through inhibition of the NF-κB signaling pathway.
8 citations
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April 2008 in “The Journal of Urology” This commentary discusses the public health implications of benign prostatic hyperplasia (BPH) and provides no new research results.
6 citations
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October 2023 in “Animal Biotechnology” This study found that a 22-bp InDel polymorphism in the FGF7 gene was significantly associated with growth traits in goats, with genotypes ID and/or II linked to better growth compared to genotype DD, indicating its potential as a molecular marker in breeding programs.
4 citations
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January 2002 This review discusses various treatments for benign prostatic hyperplasia, comparing medications like finasteride and terazosin, as well as surgical and placebo options, without presenting new clinical findings.
3 citations
,
December 2016 in “Der Urologe” 1 citations
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January 2025 in “Regenerative Biomaterials” In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.
1 citations
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May 2017 in “Urologe A” This study reports an increase in the use of tamsulosin/finasteride for benign prostatic syndrome in Germany but highlights that reliable comparisons with monotherapies are lacking due to study design deficiencies.
1 citations
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January 1997 in “ACP journal club” This study found that terazosin, finasteride, or their combination were effective in treating symptoms of benign prostatic hyperplasia.
February 2006 in “Inpharma Weekly” 29 citations
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January 2021 in “G3 Genes Genomes Genetics” This study identified a 195 bp duplication in crested chickens that causes large crest feathers and can be associated with cerebral hernia in some breeds, but not all.
5 citations
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July 2008 in “The Journal of Urology” This editorial examines the use of multiple drugs for treating lower urinary tract symptoms due to benign prostatic hyperplasia but offers no new research findings.
July 2025 in “International Journal of Health and Medicine” In this study, dual therapy with tamsulosin and solifenacin significantly improved urinary symptom severity and bladder capacity in BPH patients, but did not alter post-void residual urine volume. This supports using the combination therapy for managing LUTS, especially for storage-related symptoms, in clinical settings.
December 2021 in “Innovation in Aging” This study found that family caregivers reported significantly longer sleep onset latency compared to carefully matched non-caregiving controls, with depressive symptoms predicting poorer sleep quality among caregivers.
September 2006 in “Aktuelle Urologie” This review discusses the drug treatment of benign prostatic syndrome, highlighting the efficacy of combination therapies over monotherapies in patients at high risk for disease progression, but notes increased side effects and costs.
March 2005 in “The Nurse Practitioner” This update provides information on new drug approvals but does not offer new clinical research findings.