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      Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance

      research Regulatory T cells in skin

      110 citations , July 2017 in “Immunology”
      This review discusses the role of regulatory T cells in skin, including their impact on hair follicle regeneration, wound healing, and immune tolerance, without presenting new clinical findings.
      Androgenetic Alopecia: An Update Of Treatment Options

      research Androgenetic Alopecia: An Update of Treatment Options

      110 citations , August 2016 in “Drugs”
      Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
      Development and Homeostasis of the Sebaceous Gland

      research Development and homeostasis of the sebaceous gland

      107 citations , August 2012 in “Seminars in Cell & Developmental Biology”
      This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.
      Skin Biopsy

      research Skin biopsy

      106 citations , December 2015 in “Journal of The American Academy of Dermatology”
      This article reviews common pitfalls in biopsy site selection and technique that can lead to misdiagnosis of various skin conditions, highlighting the importance of proper biopsy practices for improving diagnostic accuracy.
      Quantitative Single-Cell Approaches to Stem Cell Research

      research Quantitative Single-Cell Approaches to Stem Cell Research

      106 citations , November 2014 in “Cell Stem Cell”
      This review discusses advanced techniques for investigating stem cell fate at the single-cell level, including lineage tracing, time-lapse imaging, and molecular profiling, but reports no new research results.
      The Proximal Promoter of the Human Transglutaminase 3 Gene

      research The Proximal Promoter of the Human Transglutaminase 3 Gene

      105 citations , February 1996 in “Journal of biological chemistry/˜The œJournal of biological chemistry”
      In this study, sequences upstream of the TGM3 gene were found to regulate epithelial-specific gene expression in keratinocytes, suggesting potential applications in gene therapy.
      Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study

      research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study

      104 citations , March 2014 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, DHT and calculated free DHT were linked to higher risks of incident cardiovascular disease and all-cause mortality in elderly men, while total testosterone and calculated free testosterone showed no such associations.
      FGF Family: From Drug Development to Clinical Application

      research FGF Family: From Drug Development to Clinical Application

      103 citations , June 2018 in “International Journal of Molecular Sciences”
      This review discusses the applications and research on fibroblast growth factors, including their use in wound healing, diabetes, and cancer, but it reports no new clinical results.
      Testosterone and Doping Control

      research Testosterone and doping control

      103 citations , June 2006 in “British journal of sports medicine”
      This review discusses the use of anabolic-androgenic steroids in sports and outlines current methods for detecting urinary steroid doping, particularly testosterone, but reports no new experimental findings.
      Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors

      research Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors

      103 citations , October 2003 in “Birth Defects Research”
      This review discusses the multifactorial etiology of hypospadias, including genetic predispositions and possible environmental factors, and highlights the need for further studies on genetic and environmental contributions to its increasing prevalence, without presenting new findings.
      Adverse Effects of Voriconazole: Over a Decade of Use

      research Adverse effects of voriconazole: Over a decade of use

      100 citations , September 2016 in “Clinical transplantation/Clinical transplantation.”
      This study highlights that prolonged voriconazole use is linked to an increased risk of aggressive cutaneous malignancies like squamous cell carcinoma, necessitating careful monitoring of drug levels to manage adverse effects.
      Sigma-1 Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced Reward

      research ς1Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced Reward

      100 citations , May 2003 in “Journal of Neuroscience”
      This study found that neuroactive steroids like DHEA and pregnenolone influence cocaine-induced appetence in mice through their interaction with the ς1 receptor, suggesting a role in individual vulnerability to addiction.
      Alopecia Areata: A Comprehensive Review of Pathogenesis and Management

      research Alopecia Areata: a Comprehensive Review of Pathogenesis and Management

      99 citations , July 2017 in “Clinical Reviews in Allergy & Immunology”
      This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
      Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis

      research Acne-associated syndromes: models for better understanding of acne pathogenesis

      99 citations , December 2010 in “Journal of The European Academy of Dermatology and Venereology”
      This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.
      Hidradenitis Suppurativa Treated With Finasteride

      research Hidradenitis suppurativa treated with finasteride

      99 citations , April 2005 in “Journal of Dermatological Treatment”
      This preliminary study suggests that finasteride may be an effective treatment option for patients with hidradenitis suppurativa, as six out of seven participants showed significant improvement.
      Androgen Excess Is the Key Element in Polycystic Ovary Syndrome

      research Androgen excess is the key element in polycystic ovary syndrome

      99 citations , August 2003 in “Fertility and Sterility”
      This paper discusses polycystic ovary syndrome with a focus on androgen excess as the primary symptom and notes that insulin resistance may contribute to it in many patients, but provides no new research findings.
      Management of Primary Cicatricial Alopecias: Options for Treatment

      research Management of primary cicatricial alopecias: options for treatment

      98 citations , May 2008 in “British Journal of Dermatology”
      This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.
      Primary Cicatricial Alopecia: Treatment Approaches and Classification

      research Primary cicatricial alopecia

      95 citations , November 2016 in “Journal of The American Academy of Dermatology”
      This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
      Stratum Corneum Dysfunction in Dandruff

      research Stratum corneum dysfunction in dandruff

      93 citations , April 2012 in “International Journal of Cosmetic Science”
      This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.