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    Glossary Benign Prostatic Hyperplasia

    non-cancerous enlargement of the prostate gland common in older men

    Benign Prostatic Hyperplasia (BPH), also known as an enlarged prostate, is a non-cancerous increase in the size of the prostate gland. This condition is common in older men and can lead to urinary symptoms such as difficulty starting urination, a weak urine stream, and frequent urination, especially at night. BPH occurs due to hormonal changes and can be managed with medications, lifestyle changes, or surgical procedures if necessary.

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    1. The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia The New England Journal of Medicine · 2003 · 1707 citations
    2. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor 2004 · 408 citations
    3. DIHYDROTESTOSTERONE AND THE PROSTATE: THE SCIENTIFIC RATIONALE FOR 5α-REDUCTASE INHIBITORS IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA 2004 · 235 citations
    4. Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5<i>α</i>-Reductase Activity and Androgen Receptor Content* 1989 · 82 citations
    5. Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using between and within patient methodology The BMJ · 2013 · 70 citations
    6. What do we know about phytotherapy of benign prostatic hyperplasia? Life Sciences · 2015 · 67 citations
    7. Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis International Journal of Andrology · 2017 · 66 citations
    8. Herbs for Benign Prostatic Hyperplasia Annals of Pharmacotherapy · 2002 · 54 citations
    9. Association of Benign Prostatic Hyperplasia with Male Pattern Baldness Urology · 1998 · 54 citations
    10. Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia Food and chemical toxicology · 2012 · 44 citations
    11. Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase Scientific Reports · 2016 · 43 citations
    12. Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia Frontiers in Pharmacology · 2020 · 35 citations
    13. Ejaculations and Benign Prostatic Hyperplasia: An Impossible Compromise? A Comprehensive Review Journal of Clinical Medicine · 2021 · 34 citations
    14. Prevalence of metabolic syndrome and its components among men with and without clinical benign prostatic hyperplasia: a large, cross-sectional, UK epidemiological study BJUI · 2015 · 31 citations
    15. Risk of erectile dysfunction associated with use of 5-α reductase inhibitors for benign prostatic hyperplasia or alopecia: population based studies using the Clinical Practice Research Datalink BMJ · 2016 · 30 citations
    16. Androgenetic alopecia as an early marker of benign prostatic hyperplasia Journal of The American Academy of Dermatology · 2011 · 28 citations
    17. Risks and side effects in the medical management of benign prostatic hyperplasia Prostate International · 2023 · 26 citations
    18. Current evidence for the involvement of sex steroid receptors and sex hormones in benign prostatic hyperplasia Research and Reports in Urology · 2019 · 26 citations
    19. Dutasteride for the treatment of benign prostatic hyperplasia Expert opinion on pharmacotherapy · 2013 · 24 citations
    20. Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in the Male Journal of the American Geriatrics Society · 1984 · 23 citations
    21. Is COVID-19 a risk factor for progression of benign prostatic hyperplasia and exacerbation of its related symptoms?: a systematic review Prostate Cancer and Prostatic Diseases · 2021 · 21 citations
    22. Comparative Study of Therapeutic Effect of Dibenyline, Finasteride, and Combination Drugs for Symptomatic Benign Prostatic Hyperplasia Urologia internationalis · 1998 · 21 citations
    23. Neuropsychological Assessment in Elderly Men with Benign Prostatic Hyperplasia Treated with Dutasteride Clinical Drug Investigation · 2018 · 20 citations
    24. Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia The World Journal of Men's Health · 2018 · 20 citations
    25. Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction Hormone Molecular Biology and Clinical Investigation · 2017 · 20 citations
    26. Corn silk extract improves benign prostatic hyperplasia in experimental rat model Nutrition Research and Practice · 2017 · 20 citations
    27. Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia Hormone Molecular Biology and Clinical Investigation · 2015 · 20 citations
    28. Ezetimibe Reduces Enlarged Prostate in an Animal Model of Benign Prostatic Hyperplasia The Journal of Urology · 2010 · 20 citations
    29. Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis PLOS ONE · 2018 · 19 citations
    30. Benign prostatic hyperplasia and male lower urinary symptoms: A guide for family physicians Asian journal of urology · 2017 · 19 citations