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Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Two new compounds were found to effectively reduce hair growth in mice.

Lasers can effectively treat pseudofolliculitis barbae, but insurance often doesn't cover it, possibly due to racial bias.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

The document reviews key historical figures and discoveries in dermatology.

The letter criticizes generalizations about older patients' abilities and calls for respectful, individualized care, while the original authors defend the need to adapt communication for those with impairments.

The cell culture medium "RPMI" might slightly improve hair graft survival, but not by a significant amount.

Using an ultrasonic liposuction machine with different cannula sizes and power settings does not change water temperature.

Dr. Zitelli emphasized that "Mohs surgery" should only be called that when one doctor does both the surgery and pathology.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Different types of skin cells play specific roles in development, healing, and cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Applying a special compound can promote hair growth without harmful side effects.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.