August 2024 in “Archives of Dermatological Research” This study suggests that proteins CHI3L1 and CXCL5, secreted by recovery-state dermal papilla cells, may promote hair growth by stimulating the proliferation of outer root sheath cells.
4 citations
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December 2024 in “Clinical Cosmetic and Investigational Dermatology” This study suggests that combining baricitinib with narrowband UV-B therapy is an effective and well-tolerated approach for treating active nonsegmental vitiligo.
January 2026 in “Updates in clinical dermatology”
3 citations
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August 2021 in “Journal of Investigative Dermatology” Baricitinib was more effective than a placebo in regrowing hair in adults with alopecia areata after 36 weeks.
86 citations
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August 2011 in “Toxicological sciences” In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.
June 2024 in “British Journal of Dermatology” This review by the British Hair and Nail Society reported that their national grand round for complex hair disorders has led to diagnosis changes in 38% of cases and has suggested novel treatments, emphasizing its role in aiding complex diagnostic and therapeutic decisions.
5 citations
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September 2023 in “Journal of Cosmetic Dermatology” This study found that c-Maf positive M2 macrophages may promote hypertrophic scar formation by enhancing the proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts through increased TGF-β1 expression.
53 citations
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January 2011 in “Diabetes” The study found that severe insulin resistance and premature diabetes are common in patients with PCNT genetic defects, primarily affecting those over four years old, while not impacting early insulin signaling in adipocytes.
July 2024 in “Journal of Investigative Dermatology” Brepocitinib reduces interferon signaling in hidradenitis suppurativa patients.
29 citations
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October 2004 in “Differentiation” Multiple mouse desmoglein 1 isoforms have distinct roles in skin and hair development.