4 citations
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January 2021 in “Journal of Clinical Medical Research” This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.
4 citations
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October 2003 in “Annales de Génétique” This study identified a mutation in the KRTHB6 gene in two monilethrix families of Indian origin, linking specific genetic variations to different severities of hair defects within the families.
3 citations
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August 1988 in “PubMed” 3 citations
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October 2021 in “Journal of Cosmetic Dermatology” This study found that topical patches containing allicin from garlic extract may be a promising and cost-effective option for treating alopecia areata, offering better aesthetic acceptance than mashed garlic.
2 citations
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January 2024 in “Proceedings of the National Academy of Sciences of the United States of America” This study developed a multiscale spatial atlas of healthy skin and basal cell carcinoma, revealing a hair follicle origin for BCC and the expansion of specific cell populations such as POSTN+ fibroblasts and RGS5+ pericytes, suggesting roles in skin cancer stroma expansion and vascular remodeling.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study created a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing a potential hair follicle origin for basal cell carcinoma and expansion of certain mesenchymal cell populations.
1 citations
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December 2022 in “Sultan Qaboos University medical journal” In this study, a machine learning framework incorporating the CatBoost algorithm accurately predicted Systemic Lupus Erythematosus in Omani patients, suggesting potential for early clinical intervention.
In this study, the ethanol extract of Tridax procumbens leaves exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria, with specific active compounds identified through GC-MS analysis that may contribute to its therapeutic potential.
May 2026 in “Journal of Personalized Medicine” In this retrospective case–control study, researchers observed that patients with alopecia areata had a higher prevalence of iron deficiency anemia compared to controls, suggesting a potential comorbidity that may require assessment and management.
This source provides medical information intended solely for licensed professionals and emphasizes that it is not a substitute for medical advice, diagnosis, or treatment decisions, which remain the responsibility of treating physicians.
November 2025 in “Journal of Pharmaceutical Research International” This study reviewed 18 studies on the effects of ustekinumab and vedolizumab on alopecia in ulcerative colitis patients, finding varied outcomes ranging from significant hair regrowth to increased hair loss, with 65.5% experiencing regrowth and potential therapy benefits needing further exploration in larger trials.
May 2025 in “Insights-Journal of Health and Rehabilitation” This study found that Aloe vera and Citrus lemon extracts demonstrated notable antibacterial effects against Propionibacterium acnes in both lab and human skin models, with combined use resulting in a 67% reduction in acne, suggesting potential for future therapeutic applications.
March 2025 in “Pediatric Rheumatology” This study found that clinicians frequently prefer cyclophosphamide over rituximab for induction therapy of childhood-onset systemic lupus erythematosus and ANCA-associated vasculitis, following a high-dose regimen recommended by the NIH.
July 2024 in “Journal of Eastern – Western Pharmacology and Pharmacy” This study found that Tribulus terrestris L. extract promoted significant hair growth and reduced skin inflammation in Wistar rats, while Urtica cannabina extract, Glycyrrhiza glabra extract, and Tribulus terrestris L. extract all led to uniform hair growth over 28 days compared to other tested extracts.
This research review found that spironolactone can significantly improve acne severity more effectively than a placebo, with 73.3% of patients reporting satisfaction despite a 26.7% rate of adverse events among the 1,548 participants studied.
July 2023 in “Journal of Controversies in Obstetrics & Gynecology and Pediatrics” This review provides an overview of polycystic ovary syndrome, including its causes, symptoms, diagnosis, and treatment strategies, and reports no new research findings.
June 2023 in “International journal on recent and innovation trends in computing and communication” This study found that ensemble machine learning models effectively predict hair fall by combining the strengths of individual algorithms, leading to higher accuracy, precision, and recall in identifying hair and non-hair fall instances compared to single algorithms.
September 2016 in “Archives of Pediatric Infectious Diseases” This case study reports that chronic skull base osteomyelitis should be considered a serious complication in patients with a history of cranial trauma or scalp procedures, despite its rarity.
305 citations
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June 2012 in “Nature” This study reports that hair regeneration in live mice involves spatially regulated stem cell divisions and requires mesenchymal interactions, observed in real-time using a novel non-invasive imaging method.
293 citations
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November 2011 in “Nature” This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.
155 citations
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March 2006 in “The American Journal of Medicine” This study found that young women with polycystic ovary syndrome have altered endothelial function associated with insulin resistance and lower adiponectin levels.
111 citations
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October 2008 in “Nature Genetics” In their study, Tim Spector and colleagues identified a new genetic association at chromosome 20p11.22 with male-pattern baldness, confirmed by the increased risk when combined with a known androgen receptor gene variant.
94 citations
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April 2018 in “Nature Genetics” This study identified more than 100 genetic loci associated with hair color variation in Europeans, explaining a significant portion of the trait's heritability and advancing understanding of hair pigmentation.
87 citations
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September 2014 in “International Journal of Molecular Sciences” This study found that the transcription factor FOXO1 plays a crucial role in wound healing by protecting keratinocytes from oxidative stress and regulating TGF-β expression.
87 citations
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May 2012 in “PLOS Genetics” This study found that early-onset androgenetic alopecia in individuals of European ancestry is significantly associated with increased odds of Parkinson's disease and is influenced by specific genetic loci, including some linked to reduced fertility.
67 citations
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May 2019 in “British Journal of Dermatology” In this study, newly diagnosed women with mycosis fungoides or Sézary syndrome and those with alopecia experienced significantly poorer health-related quality of life.
63 citations
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September 2009 in “Regenerative Medicine” This study developed a method for expanding human dermal papilla cells in vitro while maintaining their ability to induce hair growth, advancing the potential for follicular cell implantation as a treatment for hair loss.
56 citations
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January 2015 in “Circulation” This study found that finasteride treatment improved cardiac function and reduced heart failure progression in mice, suggesting it could be a potential therapy for pathological cardiac hypertrophy and dysfunction.
55 citations
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November 2010 in “Journal of Allergy and Clinical Immunology” This study found that the TLR3 L412F genetic variant is associated with severe viral infections, especially CMV, and immune dysfunction in a subgroup of chronic mucocutaneous candidiasis patients.
55 citations
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August 2003 in “Ultrasound in Obstetrics and Gynecology” This study suggests that ultrasound and color Doppler analyses may enhance the differential diagnosis of GnRH-dependent precocious puberty in girls with premature breast development or pubic hair growth.