124 citations,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
22 citations,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
December 2022 in “Journal of medical sciences and health” Examining nail biopsies is useful for diagnosing nail diseases.
10 citations,
August 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Actinic superficial folliculitis is a unique skin condition caused by intense heat and sweating.
81 citations,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
291 citations,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
221 citations,
July 2012 in “Proceedings of the National Academy of Sciences of the United States of America” BMAL1 controls skin cell growth and UV damage risk, peaking at night.
17 citations,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
18 citations,
April 2002 in “Journal of cutaneous pathology” Tiny infundibular cysts are the main lesions in chloracne, not comedones.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
November 2022 in “Journal of Investigative Dermatology” DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.
43 citations,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
20 citations,
February 1977 in “The anatomical record” Excess vitamin A changes skin and hair follicle development and affects polysaccharide distribution.
266 citations,
January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
April 2016 in “Journal of Investigative Dermatology” Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.
69 citations,
August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
18 citations,
February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
13 citations,
December 1983 in “Canadian journal of zoology” Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
2 citations,
December 2003 in “Medical electron microscopy” The skin and mucous membranes can regenerate over the basement membrane after damage, using nearby surviving cells.
7 citations,
December 2004 in “Medicine” Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.
February 2023 in “Mağallaẗ Tikrīt li-l-ʻulūm al-ṣirfaẗ/Tikrit journal of pure science” Horse skin has a layered epidermis, a dermis with hair follicles, sweat and sebaceous glands, and is supplied by small arteries.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
January 2008 in “Journal of Clinical Dermatology” Integrin alpha-6 and p63 proteins may play a role in hair loss and are important for hair growth and maintenance.
1 citations,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.
7 citations,
February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
6 citations,
April 2012 in “PloS one” The local environment is crucial for cell development in the tongue.
7 citations,
March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
46 citations,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.