research YAP And TAZ Are Essential For Basal And Squamous Cell Carcinoma Initiation
YAP and TAZ proteins are necessary for the development of two types of skin cancer.
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research Analysis of 1,25-Dihydroxyvitamin D3 Receptors in Basal Cell Carcinomas
Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
research Scalp Basal Cell Carcinoma: A Different Entity?
Scalp basal cell carcinoma may be more aggressive and harder to treat than other types, requiring special attention and further research.
research Malignant Epithelial Tumors: Part II. Therapy and Prevention
The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.
research Mommy, Where Do Tumors Come From? The Origins of Basal Cell Carcinomas
Some skin tumors may start from hair follicle stem cells.
research Sox9 Expression in Canine Epithelial Skin Tumors
Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
research Cutaneous Neoplasms in Myotonic Dystrophy Type 1
People with myotonic dystrophy type 1 tend to develop basal cell carcinoma at a younger age but not more frequently than others.
research Importance of Vascular Patterns in the Dermoscopy Recognition of Cutaneous Tumors
Vascular patterns in dermoscopy help tell apart malignant and benign skin tumors.
research Stromal Re-Organization in Hair Follicle Development and Cancer Suppression
Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
research P62 Pre-Clinical Pharmacological and Skin Penetration Profile of LDE255, a Novel and Specific Smoothened Antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research Desmoplastic Trichoepithelioma: Histopathologic and Immunohistochemical Criteria for Differentiation of a Rare Benign Hair Follicle Tumor From Other Cutaneous Adnexal Tumors
The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Expression of Potential Dermal Progenitor Cell Markers in the Tumor and Stroma of Skin Adnexal Malignant and Benign Tumors
Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
research Dermoscopy of Cutaneous Adnexal Tumors: A Systematic Review of the Literature
Most cutaneous adnexal tumors examined were benign and resembled common skin tumors.
research The Extracellular Matrix Dictates Regional Competence for Tumor Initiation
The extracellular matrix affects where tumors can start in the body.
research Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis
Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
research The Effects of Sonic, Desert, and Indian Hedgehog Signaling in Skin
Shh and Dhh affect skin development and can cause tumors, while Ihh does not.
research Scalp Lesions: Causes, Symptoms, and Treatments
Different scalp conditions can lead to hair loss or tumors, with treatments varying from creams to surgery; early detection is crucial.
research Infections, Infestations, and Neoplasms of the Scalp
The chapter explains common scalp conditions, including infections, infestations, and tumors.
research Other Questions on Basaloid Follicular Hamartoma
Basaloid follicular hamartoma's appearance can be similar to other skin conditions, and diagnosis should consider both the look and behavior of the tumor.
research Tracing the Cellular Origin of Cancer
Understanding where cancer cells come from helps create better prevention and treatment methods.
research The Rotterdam Study: 2012 Objectives and Design Update
The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
research Usefulness of Dermoscopy to Provide Accurate Assessment of Skin Cancers
Dermoscopy is an effective tool for accurately detecting skin cancers.
research A Case of Multiple Trichoepitheliomas Associated with Alopecia Areata and Systemic Lupus Erythematosus
Autoimmune conditions can be linked to trichoepitheliomas, with treatment focusing on cosmetic concerns.
research Loss of TET2 Tips the Scales Toward Tumorigenesis
Loss of TET2 increases the risk of skin and oral cancer.
research A Case of Trichogerminoma: A Rare Cutaneous Follicular Neoplasm
Trichogerminoma is a rare, benign skin tumor from hair cells, with a small risk of becoming cancerous.
research Dermatopathology Update: 2013 Advancements in Diagnosis and Treatment of Skin Diseases
The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.
research Basal Cell Carcinoma, Hedgehog Signaling, and Targeted Therapeutics: The Long and Winding Road
New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma
Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.