December 2025 in “The Journal of Cell Biology” This study found that keratin 15 lacks the ability to sequester YAP1 in keratinocytes effectively, unlike keratin 14, and suggests that a higher K15:K14 ratio may promote a progenitor state and inhibit differentiation in epidermal keratinocytes.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” This report presented a case of a patient with basal cell carcinoma and systemic lupus erythematosus who was treated successfully with sonidegib, showing positive outcomes without worsening lupus activity, despite lacking documented clinical use of sonidegib in such patients.
October 2025 in “Portuguese Journal of Dermatology and Venereology” In this case report, a 54-year-old woman with a rare desmoplastic trichoepithelioma presented with clinical features resembling basal cell carcinoma, highlighting the importance of histopathological and immunohistochemical analyses for accurate diagnosis.
September 2025 in “Cancer Innovation” This study argues for "clinical trial re-innovation," highlighting new designs like basket, umbrella, and platform trials that incorporate biomarker technologies to meet the dynamic needs of precision medicine, potentially enabling more effective, patient-specific treatments and overcoming limitations of traditional disease-centered trials.
September 2025 in “Frontiers in Medicine” This study assessed the effectiveness of various combinations of minoxidil with other agents for androgenetic alopecia, finding that platelet-rich plasma and basic fibroblast growth factor combined with minoxidil significantly increased hair density, while different combinations were optimal depending on gender.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that combining minoxidil with platelet-rich plasma and basic fibroblast growth factor was the most effective treatment for increasing hair density in androgenetic alopecia, showing a significant improvement over minoxidil alone.
September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that human dermal papilla cells are surrounded by a basement membrane-like extracellular matrix, which maintains their aggregated structure without strong cell‒cell contacts.
In this case study, researchers reported the first documented instance of malignant transformation of congenital triangular alopecia into basal cell carcinoma in a 48-year-old woman, underscoring the importance of assessing long-standing alopecic areas for malignancy.
August 2025 in “Journal of IMAB - Annual Proceeding (Scientific Papers)” This study describes a successful reconstructive A-T flap surgery on a 74-year-old male with a 35mm basal cell carcinoma on the scalp, resulting in a 50mm defect, with no complications and optimal functional and cosmetic outcomes reported.
July 2025 in “Journal of Investigative Dermatology” Complex basal cell carcinomas need personalized treatment due to unique genetic mutations.
June 2025 in “Indian Journal of Dermatology” This article reports a case of late onset linear and unilateral basaloid follicular hamartoma in an elderly male, highlighting the clinical presentation, histopathological findings, and planned treatment approach.
May 2025 in “Journal of Dermatological Treatment” Results are not provided in this abstract. It discusses a comparison between the efficacy of minoxidil alone and in combination with low-level laser therapy for treating androgenic alopecia.
January 2025 in “International Journal of Dermatology” This study observed that indigenous South Africans with natural afro-textured hair have lower hair densities, varying shaft diameters, and distinct follicular unit patterns compared to other racial groups, with significant gender differences in some parameters, highlighting the need for tailored reference values in clinical settings.
November 2024 in “The Journal of Cell Biology” This study revealed that basement membrane dynamics are crucial to hair follicle development, influencing progenitor cell behavior and cell division patterns in developing mouse hair follicles.
September 2024 in “AYUSHDHARA” This article examines the Ayurvedic approach to treating polycystic ovarian syndrome with Basti therapy and discusses its potential for both lean and obese phenotypes, but provides no new clinical results.
This case study indicates that older patients with NMOSD may show favorable clinical improvements with aggressive treatment, even when the intervention is initiated later in the disease course.
July 2024 in “Journal of Investigative Dermatology” Substance P helps restore skin thickness and cell renewal when sensory nerves are reduced.
In this report, two pediatric cases of solitary basaloid follicular hamartoma, a rare benign skin malformation often misdiagnosed, were documented using dermoscopy, highlighting its clinical diversity and the need for accurate diagnosis.
December 2023 in “The journal of cell biology/The Journal of cell biology” This study developed the mTurquoise2-Col4a1 mouse model and used fluorescent tagging of collagen IV to offer new insights into basement membrane dynamics during hair follicle budding, revealing that basement membranes are flexible and stable structures in developing skin tissue.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used a novel fluorescent tagging method in mice to observe collagen IV dynamics during hair follicle development, revealing that alterations in basement membrane turnover can influence epithelial progenitor cell behavior and organ morphology by affecting cell proliferation and movement.
This study compared the safety and effectiveness of 5% cetosomal minoxidil to 5% alcohol-based minoxidil in Indian men with androgenetic alopecia, finding that cetosomal minoxidil had improved safety and similar efficacy, making it a potentially better option for those sensitive to alcohol-based formulations.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study describes the use of a genetically engineered mouse model, mTurquoise2-Col4a1, to fluorescently label collagen IV and observe basement membrane dynamics during skin development, revealing its stability and pliability during rapid growth phases.
May 2023 in “Journal of Cosmetic Dermatology” This prospective randomized controlled trial found that combining platelet-rich plasma plus basic fibroblast growth factor injections with topical minoxidil significantly improves hair count and growth rate in androgenetic alopecia patients compared to either treatment alone.
In preclinical studies, topical CUR61414 reduced Hh signaling and shrank BCCs in mice, but this study found no clinical efficacy in human superficial or nodular BCCs.
January 2023 in “Fashion and textiles” This study found that hair dyed with anionic basic hair dye lost more color after shampooing compared to cationic and nonionic dyes, with alkaline shampoo increasing this effect.
January 2023 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” This study found that a mixed extract of N. jatamansi, O. basilicum, and C. sativus, particularly when extracted via steaming and ultrasonic methods, increased antioxidant content, stimulated melanin production for black hair, and promoted hair growth in mouse models, while maintaining high cell viability.
May 2022 in “Liver transplantation” This source does not report original research findings but reviews the mechanisms and challenges of immune response and immunosuppressive management in liver transplantation.
March 2022 in “Veterinary dermatology” This case report provides the first evidence of clinical and histopathological findings of cutaneous diffuse basaloid follicular hamartomas in a young domestic short hair cat.
June 2021 in “Research Square (Research Square)” This article reviews current research on epidermal stem cells and differentiation, presenting models of basal layer composition, but reports no new experimental findings.
May 2021 in “Pakistan Journal of Medical and Health Sciences” This study found that among Pakistani men with hair loss, the M type pattern was the most prevalent according to BASP classification.