This book reviews evidence-based medicine practices in obstetrics and gynecology but reports no new clinical findings.
May 2018 in “University Library - University of Saskatchewan (University of Saskatchewan)” This study found that in women with polycystic ovary syndrome, a pulse-based diet was more effective than the TLC diet at improving insulin sensitivity and cardiometabolic risk factors, although both diets improved PCOS-specific health outcomes.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” In this study, researchers tested various nanocarrier characteristics and found they could enhance drug delivery to specific skin areas and immune cells, potentially improving treatments for skin conditions by targeting drugs effectively.
January 2018 in “프로그램북(구 초록집)” This study found that ceramide-based essence cream, particularly those with stearyl and stearyl-cholesterol, improved the ultrastructure of damaged hair cuticles.
December 2017 in “British Journal of Dermatology” Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.
October 2017 in “Doctoral thesis, UCL (University College London).” This study developed and tested nanostructured lipid carriers for topical dutasteride delivery, finding them stable, low in cytotoxicity and non-irritating, with no drug permeation through pig ear skin over 48 hours.
September 2017 in “Springer eBooks” FUE hair transplants have improved to give more natural results with less scarring and pain.
April 2017 in “Journal of Pharmaceutical Investigation” In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.
Hair restoration techniques have improved based on scientific evidence.
November 2015 in “Journal of the Korea Academia-Industrial cooperation Society” This study established a stable cell line for CRF1 receptor screening, which can be used to develop functional cosmetics and modulators potentially affecting hair re-growth.
This chapter reviews various treatments for hirsutism, including antiandrogens, finasteride, eflornithine, and epilation methods, but reports no new clinical results.
January 2014 in “Cosmoderma” This review examines the effectiveness of current treatments for androgenetic alopecia, offering plastic surgeons evidence-based guidance for choosing safe and effective options, but reports no new results.
This literature review analyzes existing studies on breast cancer management and underscores the need for improved psychological support throughout diagnosis, treatment, and remission.
This review discusses hair transplantation as a permanent treatment for androgenetic alopecia, emphasizing the importance of stabilized hair loss, skilled surgical teams, and realistic expectations, while calling for more quantitative evidence from controlled trials.
This review discusses cyclosporine A's mechanisms of action and side effects compared to tacrolimus in renal transplantation, but it reports no new experimental results; the authors highlight implications for cardiovascular risk management.
January 1983 in “Elsevier eBooks” This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.
April 2023 in “Journal of Investigative Dermatology” This study assessed an AI-based mobile app for evaluating androgenetic alopecia severity, finding that it achieved 94% accuracy compared to human dermatologists, while participants often underestimated their own hair loss severity.
April 2023 in “Journal of Investigative Dermatology” This study found that autologous cell-based therapy using dermal sheath cup cells showed a moderate increase in hair volume in patients with pattern hair loss, particularly in women.
February 2023 in “European Journal of Medical Research” This study identified several drugs that may be potential candidates for repurposing as anti-hyperhidrosis treatments, based on their association with hypohidrosis or anhidrosis in the FDA Adverse Event Reporting System.
July 2021 in “Journal of reports in pharmaceutical sciences” This study evaluated a new aqueous-based nanosuspension of minoxidil for treating androgenetic alopecia and reported it was as effective as the commercial product but had better safety and tolerability, potentially improving patient compliance.
October 2020 in “Journal of Pharmaceutical Sciences” This study found that using gallate-containing formulations like EGCG or tannic acid increased the solubility and controlled release of finasteride in microspheres, enhancing its dermal penetration in pig skin by 10 to 50 times compared to a control.
April 2020 in “Dermatology and therapy” In this study, the novel 5% minoxidil formulation significantly increased scalp hydration and decreased redness in Indian men with androgenetic alopecia compared to alcohol-based formulations.
1108 citations
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January 2018 in “Dalton transactions” This review discusses the multiple severe side effects of cisplatin, carboplatin, and oxaliplatin in cancer treatment and reports no new clinical results; the authors emphasize the need for careful monitoring and supportive care to manage these effects.
517 citations
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February 2010 in “Materials” This review discusses the history and development of keratin biomaterials for biomedical uses, highlighting their biological activity and biocompatibility, and provides no new research findings.
263 citations
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February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.
233 citations
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November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores androgen metabolism in the skin, highlighting enzyme localization and potential implications for treating androgen-dependent skin conditions, but it reports no new clinical results.
188 citations
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May 2009 in “Plant physiology” This study identified 19 specific genes involved in root hair growth and morphogenesis in Arabidopsis, using a combination of computational and experimental methods.
178 citations
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August 2016 in “Advances in wound care” This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
162 citations
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October 2014 in “Autoimmunity reviews” This review discusses alopecia areata, highlighting its autoimmune aspects, environmental triggers, and current treatment options, but reports no new clinical results; recent studies suggest JAK pathway intervention may offer therapeutic potential.
158 citations
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January 2015 in “Artificial Intelligence in Medicine” This study found that DrugNet, a network-based prioritization method, effectively improves drug repositioning tasks, achieving high performance in validation tests and clinical trial comparisons.