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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Doctors need to be better prepared to assess and treat obesity in patients.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

The article concludes that advancements in hair cosmetics require dermatologists to stay informed about products and their potential risks, including allergies and higher risks for hairdressers.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.

Some alternative treatments for hair loss might work, but more research is needed.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

Women with high androgen levels may have more severe COVID-19 symptoms.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.

Spironolactone is effective and safe for treating acne with minimal side effects.

The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.