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360-390 / 1000+ resultsresearch Arabidopsis VILLIN4 is involved in root hair growth through regulating actin organization in a Ca2+‐dependent manner
This study demonstrated that AtVLN4 plays a role in root hair growth by regulating actin organization in a calcium-dependent manner.
research Where WNT the Hair
This review discusses genetic factors associated with androgenetic alopecia, particularly the roles of the AR/EDA2R locus and histone deacetylases, but it does not present new clinical results.
research Dodatek A: Model matematyczny AL/RC/ASE. Functional Androgen Axis (FOA) - wersja operacyjna v1.2
This research presents the Dodatek A model, elaborating on androgen function through new mathematical indices and methodological improvements, shifting focus from serum hormone concentrations to system interactions to better describe androgen activity comprehensively.
research Efficacy of Asymmetric siRNA Targeting Androgen Receptors for the Treatment of Androgenetic Alopecia
This study found that intradermal injection of a cell-penetrating, AR-targeting asiRNA promoted hair growth and reduced androgen receptor expression in mouse models of androgenetic alopecia, suggesting its therapeutic potential.
research Ultrastructural localization of hair keratin homologs in the claw of the lizard Anolis carolinensis
In this study, researchers found that alpha-keratin homologs similar to those in mammalian hair are present in the claws of the lizard Anolis carolinensis, suggesting a structural role during claw formation.
research Artefactual Skin Disorder: Exploring Clinical Features, Psychiatric Associations, and Contemporary Treatment Approaches: a Narrative Review
This paper outlines the clinical features of artefactual skin disorder, emphasizing the complexities in diagnosing the self-inflicted lesions that patients deny, and underscores the importance of integrating dermatological, psychiatric, and psychological treatment approaches.
research Sarcoptic mange outbreak decimates South American wild camelid populations in San Guillermo National Park, Argentina
This study reports that a sarcoptic mange outbreak, likely originating from mange-infected llamas from a governmental program, dramatically reduced vicuña and guanaco populations in San Guillermo National Park, Argentina.
research Successful hair regrowth in an acute diffuse form of alopecia areata during oral tacrolimus treatment in a patient with rheumatoid arthritis
Oral tacrolimus helped a rheumatoid arthritis patient regrow hair lost due to alopecia areata.
research Videodermoscopic analysis of the skin of purebred arabian horses and polish sport horses.
In this study, researchers observed that Purebred Arabian horses had significantly thicker hair in most assessed body areas compared to Polish Sports horses, indicating that breed should be considered in evaluations of equine skin and hair characteristics.
research Economic Burden of Alopecia Areata in the Kingdom of Saudi Arabia from a Societal Perspective: A Cost-of-Illness Analysis
This analysis highlights the substantial financial burden AA creates in Saudi Arabia, emphasizing the importance of early diagnosis and standardized treatment protocols to improve resource allocation and patient outcomes.
research Agouti and Agouti-related Protein: Analogies and Contrasts
This review discusses the roles of the Agouti and Agouti-related proteins in pigmentation and energy regulation and reports no new experimental findings.
research Archeological hair in paleobiological research
This study used Scanning Electron Microscopy to analyze South American mummy hair, revealing high levels of sulfur, calcium, and potassium, highlighting SEM's utility in anthropological investigations.
research Increased expression of Ectodysplasin A2 Receptor EDA2R is the most remarkable and ubiquitous aging-related transcriptional hallmark
This study found that increased mRNA expression of the Ectodysplasin-A2-Receptor, observed across multiple species and tissues, may exacerbate inflammation during aging, suggesting potential benefits of blocking EDA2R/EDA-A2 signaling.
research Androgen Receptor Actions Modify Skin Structure and Chemical Carcinogen-induced Skin Cancer Susceptibility in Mice
This study found that androgen receptor inactivation in male and female mice reduced susceptibility to DMBA-induced skin cancer, but the effect varied by the carcinogenesis model.
research Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene
This study demonstrated that an AR-EGFP transgene can restore AR function and fertility in Sertoli cell-specific AR knockout mice, highlighting its potential use in understanding androgen receptor functions.
research Alopecia in Bats from Tropical Urban Islands
This study conducted in Batam City found a 10.79% prevalence of alopecia among 417 captured bats across seven species, with higher rates in fragmented urban forests associated with anthropogenic pressures, highlighting the influence of habitat conditions on bat health.
research Detection of mange-like skin lesions on snow leopard (Panthera uncia) and prey species in Kyrgyzstan
This study found that camera trap images revealed mange-like skin lesions in snow leopards and other species in Kyrgyz reserves, with detection rates varying widely and raising concerns about disease spread.
research Microsporum gypseum isolated from a feline case of dermatophytosis
This case report describes a rare instance of dermatophytosis in a young cat caused by Microsporum gypseum, confirmed by molecular analyses to be Arthroderma gypseum.
research CAG polymorphism in the androgen receptor gene in women may be associated with nodulocystic acne
This study found that the count of CAG trinucleotide repeats in the androgen receptor gene may be associated with acne in female patients without hyperandrogenism.
research Granulomatous Alopecia Areata: A Rare Report With a Review
This case report describes a rare instance of sarcoidal granulomatous alopecia areata in a 42-year-old man, with histopathological findings suggesting inflammation but ruling out causes like tuberculosis and syphilis, resulting in treatment with tofacitinib.
research 0652 The emerging fungal pathogen Candida auris induces IFNγ to colonize mammalian hair follicles
Candida auris uses the immune response to colonize hair follicles.
research Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance
This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.
research Significance of the polyglutamine tract polymorphism in the androgen receptor
This review discusses the association between androgen receptor CAG repeat polymorphism and several health conditions, including Kennedy’s disease and urologic disorders, without reporting new clinical results.
research GWASs Identify Genetic Loci Associated with Human Scalp Hair Whorl Direction
Certain genes influence the direction of hair whorls on the scalp.
research ABATE CLANDESTINO DE BOVINOS: RISCOS E CONSEQUÊNCIAS
This case report documents a dog with dermatophytosis, caused by the fungus Microsporum canis, presenting symptoms like alopecia in the neck and ear, highlighting the condition's prevalence in tropical and temperate climates and its zoonotic nature.
research Pre-receptor regulation of the androgen receptor
This study identified enzymes responsible for regulating androgen action in the human prostate, suggesting that inhibiting AKR1C2 or RL-HSD may have therapeutic potential in androgen insufficiency or benign prostatic hyperplasia, respectively.
research A locus on distal chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice
This study identified a new genetic locus, ahl4, on distal Chromosome 10 that contributes to the early-onset, severe hearing loss in A/J mice compared to B6 mice.
research Dermatologists’ Perspectives and Real-World Assessment of Alopecia Areata Severity, Burden, and Healthcare Resource Utilization in Adults in the Kingdom of Saudi Arabia
This study conducted in the Kingdom of Saudi Arabia reported that severe alopecia areata presents significant treatment challenges due to limited therapies, leading to substantial impacts on patients' quality of life, mental health, and economic burdens.
research 1343 Efficacy of asymmetric siRNA targeting androgen receptor for the treatment of androgenetic alopecia
This study found that intradermal injection of a specially designed RNA molecule, cp-asiAR, successfully reduced androgen receptor levels and promoted hair growth in a mouse model of androgenetic alopecia, while also improving hair follicle characteristics in ex vivo human scalp tissues without significant toxicity.