19 citations
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September 2013 in “Molecular Medicine Reports” In this study, researchers developed a method to efficiently derive contractile smooth muscle cells from human hair follicle stem cells using TGF-β1 and PDGF-BB, which may advance vascular tissue engineering.
15 citations
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January 2014 in “BioMed Research International” This review discusses the concept of drug repositioning and highlights fragmin and protamine as emerging biomaterials for tissue engineering and regenerative medicine, but it reports no new clinical results.
8 citations
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January 2015 in “Journal of Cutaneous Medicine and Surgery” This review discusses the development of surgical hair restoration techniques and highlights the potential of hair follicle cell cloning to address current limitations.
4 citations
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January 2014 in “BioMed Research International” This special issue reviews advancements in engineering cell microenvironments for tissue engineering, highlighting various studies on interventions like silk fibroin and platelet-rich plasma, but presents no new empirical findings.
3 citations
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November 2020 in “Clinical, Cosmetic and Investigational Dermatology” This review summarizes the current treatment modalities for frontal fibrosing alopecia and provides a practical guide for clinicians, but reports no new clinical results.
This review reports that hair follicles are dynamic neuro-immuno-endocrine organs with intrinsic signaling pathways, which play a crucial role in hair disorders like alopecia. It highlights emerging regenerative approaches targeting these pathways for hair restoration.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.
September 2025 in “Frontiers in Medicine” This study assessed the effectiveness of various combinations of minoxidil with other agents for androgenetic alopecia, finding that platelet-rich plasma and basic fibroblast growth factor combined with minoxidil significantly increased hair density, while different combinations were optimal depending on gender.
In this narrative review, researchers evaluated existing literature on the treatment of frontal fibrosing alopecia, finding that while no curative treatment exists, clinical improvements can be achieved through personalized and combined therapy approaches.
March 2024 in “International journal of pharmaceutical sciences and drug research” In this review, the authors explored current and novel treatment options for androgenetic alopecia, noting both FDA-approved pharmacologic treatments like Minoxidil and Finasteride and various non-pharmacologic and surgical methods, including hair transplantation and scalp micro-pigmentation.
August 2010 in “The Journal of Dermatology” The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.
99 citations
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July 2017 in “Clinical Reviews in Allergy & Immunology” This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
February 2026 in “Bioengineering” This study concluded that repeated platelet-rich plasma injections provided greater and more consistent improvements in stress urinary incontinence symptoms compared to pelvic floor muscle training.
25 citations
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August 2022 in “Frontiers in Reproductive Health” This review discusses the use of platelet-rich plasma injections for treating erectile dysfunction, noting the potential for regenerative medicine to reverse or halt disease progression, but it reports no new clinical results.
March 2026 in “Journal of Ovarian Research” This review explores the potential of platelet-rich plasma therapy for early ovarian reserve decline and premature ovarian insufficiency, indicating some ovarian function improvements in initial studies but highlighting the need for further research.
2 citations
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December 2023 in “Advanced science” This review discusses the roles and mechanisms of glycosaminoglycans in wound healing and presents challenges and potential applications for GAG-based biomaterials without reporting new experimental results.
January 2026 in “Archives of Dermatological Research”
December 2020 in “Journal of The American Academy of Dermatology” In this study, machine learning models showed high accuracy in predicting therapeutic outcomes for female pattern hair loss, highlighting the significant impact of age of onset and condition duration on treatment response.
2 citations
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July 2025 in “Journal of Cosmetic Dermatology” This research discusses the shift in cosmetic dermatology towards integrating regenerative medicine, AI, and personalized care, highlighting their potential to improve aesthetic outcomes and skin function while considering ethical and regulatory challenges.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study identified specific trichoscopic signs of secondary post-traumatic cicatricial alopecia in patients with mine-explosive injuries and burns and evaluated the effectiveness of hair transplantation procedures combined with PRP therapy, finding an average hair survival rate of 84.1% one year post-surgery.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that trichoscopic examination revealed specific signs of secondary post-traumatic cicatricial alopecia in patients with mine-explosive injuries and burns, and reported an 84.1% hair survival rate following transplantation and PRP therapy, with marked improvements in scalp condition after 12 months.
6 citations
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May 2025 in “Cosmetics” This review synthesizes research on solar radiation's multifaceted effects on skin and recent advancements in sunscreen technology, including formulation, testing methods, and the use of AI, to inform future sun protection product development.
December 2025 in “Pharmaceutics” This review highlights new perspectives in genomics and epigenomics for skin rejuvenation, comparing innovative strategies like senolytics and DNA repair modulators with classical treatments, and emphasizing the importance of tailoring therapies using individual genomic profiles for personalized anti-ageing approaches.
48 citations
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March 2020 in “Stem Cell Research & Therapy” This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.
17 citations
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October 2023 in “Molecules” In laboratory and artificial skin model experiments, this study found that plant-derived PDRN from Korean ginseng effectively promoted skin cell regeneration and strengthened the skin barrier, suggesting a sustainable alternative to animal-derived PDRN.
July 2026 in “Journal of the American Academy of Dermatology” CRT is more effective than oral minoxidil alone for treating hair loss.
April 2024 in “Journal of composites science” This review details how hydrogel composites play crucial roles in regenerative medicine, tissue engineering, and drug delivery systems, highlighting innovations in these applications and addressing challenges like bioactivity, biomechanical compatibility, and controlled drug release.
25 citations
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February 2025 in “Frontiers in Bioengineering and Biotechnology” This review covers advancements in skin repair and rejuvenation technologies, highlighting potential benefits of stem cell therapy, bioengineered skin substitutes, PRP, exosome therapies, and gene editing for conditions such as chronic wounds and genetic disorders, though challenges in accessibility, safety, and long-term effectiveness remain.
5 citations
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March 2022 in “Frontiers in Medicine” This review analyzed 17 recent clinical trials on platelet-rich plasma for androgenetic alopecia but reports no new clinical results; the authors seek a consensus on optimal PRP use.
2 citations
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September 2025 in “Journal of Clinical Medicine” This review highlights the potential of regenerative medicine therapies, such as biologics and emerging technologies, to significantly impact aesthetic and reconstructive procedures in plastic surgery and dermatology.