1 citations
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January 2026 in “Frontiers in Cell and Developmental Biology” This study reviews the transformative role of artificial intelligence in biomaterial design, highlighting its ability to reduce costs through virtual screening, enhance material performance, and predict biological interactions to advance personalized and precision medicine.
1 citations
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September 2025 in “Clinical Cosmetic and Investigational Dermatology” This narrative review highlights the potential of autologous adipose mesenchymal stem cell-derived exosomes (AMSCs-Exos) in anti-skin aging, noting their superior biocompatibility and manufacturing advantages while stressing the need for standardized production protocols to overcome existing application challenges.
December 2025 in “Skin Appendage Disorders” Patients found AI helpful for alopecia diagnosis but want it to support, not replace, doctors.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
March 2025 in “Plastic & Reconstructive Surgery Global Open” This study reported that participants applying topical human platelet exosome extract serum experienced significant improvements in hair volume, density, scalp coverage, and overall hair health compared to a placebo, and no adverse effects were observed.
1160 citations
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November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
60 citations
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December 2021 in “Cytokine & growth factor reviews” This review discusses the regenerative applications of platelet-rich plasma across various medical fields and reports no new clinical results, highlighting the need for further research into standardizing its preparation and use.
56 citations
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January 2021 in “Clinical and Experimental Medicine” This review highlights the challenges in treating alopecia areata, noting that current therapies often lead to relapse and have uncertain long-term effectiveness; it also points to potential future treatments such as JAK-STAT inhibitors and PRP.
29 citations
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December 2019 in “Transfusion and Apheresis Science” This review discusses platelet-derived bio-products for tissue regeneration in various medical fields and reports no new clinical results; it highlights the need for a standardized classification to compare clinical outcomes effectively.
27 citations
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January 2020 in “Experimental Dermatology” This review discusses the role of immune cells in mammalian hair cycle control and highlights their potential relevance to human hair cycling disorders, reporting no new clinical findings.
23 citations
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September 2018 in “Dermatologic Therapy” This article explains that skin microneedling promotes skin regeneration by creating microinjuries, which stimulate collagen and elastin production, making it effective for treating various skin issues with high effectiveness, limited side effects, and a short recovery time.
12 citations
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March 2018 in “Bioengineering” This review discusses the use of non-transfusional hemocomponents in surgical procedures for tissue regeneration and reports no new empirical findings.
10 citations
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January 2016 in “Elsevier eBooks” This chapter reviews the role of nanoparticles in wound healing, exploring current therapies, developments, and future directions, but reports no new clinical results.
7 citations
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December 2018 in “Discoveries” This review discusses the potential benefits and limitations of platelet-rich plasma in wound healing, especially for skin wounds, and reports no new experimental findings.
2 citations
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November 2023 in “Journal of Cosmetic Dermatology” This review examines the bibliometric landscape of research on platelet-rich plasma in cosmetic therapy from 2001 to 2022 and reports no new clinical findings, but highlights research trends and future directions.
1 citations
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January 2025 in “Veterinary Medicine International” This review found promising benefits of platelet-rich plasma for treating ocular surface diseases in animals, but methodological flaws currently preclude recommending it as standard care.
1 citations
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September 2024 in “Frontiers in Cell and Developmental Biology” This study found that platelet-rich fibrin provides more sustained therapeutic effects than platelet-rich plasma in inhibiting apoptosis and enhancing proliferation and migration of human endometrial stromal cells.
July 2026 in “Frontiers in Medicine” This review explores the evidence for platelet-rich plasma, exosomes, and other regenerative therapies as adjuncts in hair transplantation, finding that PRP has the most support, but highlights the need for standardization and transplantation-specific studies.
June 2026 in “International Science Journal” This study reviewed recent advances in regenerative technologies for aesthetic and reconstructive medicine and found that adipose-derived stem cells and platelet-rich plasma are well-established for tissue repair due to their safety and effectiveness, while emerging technologies like exosome-based therapies hold future potential.
April 2026 in “Indian Journal of Dermatology” This study concluded that platelet-rich plasma therapy was as effective as intralesional triamcinolone acetonide in treating localized alopecia areata on the scalp.
October 2025 in “Asian Journal of Oral Health and Allied Sciences” In this case report, a 28-year-old male with androgenetic alopecia showed improved hair density and shaft thickness after four monthly sessions of autologous growth factor concentrate injections, with no adverse effects and high patient satisfaction, suggesting the treatment’s promise as a safe and effective option.
September 2025 in “Journal of Cosmetic Dermatology” This study found that both PRP injections and microneedling treatments significantly improved hair count and thickness in patients with androgenetic alopecia, without significant differences between the two methods. Microneedling also enhanced patient satisfaction and treatment tolerance.
July 2025 in “Cosmoderma” This review discusses the various applications of platelet-rich plasma in dermatology, particularly its potential in esthetic dermatology and hair and scalp conditions, but reports no new clinical findings.
April 2025 in “Diagnostics” This review synthesizes data suggesting that managing inflammation and oxidative stress may enhance the effectiveness of PRP therapy for hair regeneration, though standardizing PRP protocols remains challenging.
November 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study reported two cases of severe multifocal alopecia areata successfully treated with a combination of topical minoxidil and intralesional platelet-rich plasma, resulting in significant hair regrowth, though further controlled trials are needed to confirm these findings.
October 2024 in “Cosmetics” This study found that while most women reported aesthetic improvement after PRP facial injections, objective skin analyzer data showed no significant changes, but midface volume improvement was more likely in those with lower platelet counts and higher estradiol levels.
January 2024 in “Journal Of Advanced Zoology” This review examines platelet-rich plasma for tissue repair and regeneration, reporting promising but inconclusive efficacy across applications; the authors stress the need for rigorous clinical trials.
This study concluded that using Plasma gel and PRP as autologous collagen biostimulators improved acne scars and skin density, demonstrating efficiency and safety for facial rejuvenation in clinical evaluations including patient satisfaction.
January 2009 in “Side effects of drugs annual” This chapter reviews drugs affecting blood coagulation and details the increased hemorrhage risk associated with warfarin interactions, liver disease, heart failure, and antiphospholipid antibodies but reports no new clinical results.
42 citations
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February 2021 in “Signal Transduction and Targeted Therapy” This review discusses potential cell sources and bioengineering strategies for regenerating hair follicles with functional cycling, reporting no new results.