39 citations
,
June 2023 in “Advanced Materials” This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.
35 citations
,
November 2020 in “Experimental Dermatology” This study found that upper wound fibroblasts are crucial for hair follicle regeneration during wound healing and suggests that these cells, along with papillary fibroblasts, migrate within the wound.
27 citations
,
January 2012 in “Current Topics in Microbiology and Immunology” This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
26 citations
,
December 2011 in “Journal of Investigative Dermatology” This review discusses major advances in understanding inherited hair diseases through genetic research and reports no new clinical results; the authors emphasize the potential for new preventive and therapeutic tools.
21 citations
,
November 2017 in “Scientific Reports” This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.
21 citations
,
March 2015 in “Journal of The American Academy of Dermatology” In this study, five out of six patients treated with vemurafenib for metastatic melanoma experienced hair loss, which improved after topical steroid treatment.
21 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” This review discusses a clinical approach to diagnosing alopecia through patient history and clinical findings, but it reports no new clinical results.
18 citations
,
October 2022 in “Biomedicines” This review discusses the role of anti-Müllerian hormone in polycystic ovary syndrome and its male equivalent, but reports no new clinical findings; it suggests further investigation is needed into male relatives' reproductive function.
18 citations
,
December 2002 in “European Journal of Biochemistry” This study found that the MsPG3-GFP fusion protein accumulates at the growing root hair tips in Medicago plants, suggesting its role in tip growth during symbiosis.
17 citations
,
February 2015 in “Cell Death and Disease” This study found that inhibiting AP1 transcription factor activity in the suprabasal epidermis of mice alters keratinocyte gene expression, reducing barrier integrity and mimicking human keratoderma.
14 citations
,
April 2019 in “Genes” This study identified a genetic locus associated with coat type in domestic dogs, showing certain variants linked to single-coated breeds and suggesting potential regulatory roles.
13 citations
,
March 2023 in “International Journal of Molecular Sciences” This study found that lower levels of Gas6 and sAxl were independently associated with a history of hair loss following COVID-19, which spontaneously resolved in most cases.
12 citations
,
January 2007 in “Current problems in dermatology” This review discusses the impact of various exogenous agents on hair, such as cosmetics and radiation, but reports no new experimental results.
11 citations
,
August 2017 in “Journal of Chromatographic Science” This study established a rapid and accurate ultra-performance liquid chromatographic method for chemical fingerprinting and analyzing Platycladi cacumen, effectively distinguishing batches based on geographical and climatic conditions.
9 citations
,
September 2010 in “Dermatologic therapy” This study found that combined therapy with cetirizine and topical steroids stabilized inflammation in most patients with lichen planus pilaris, though one patient experienced cardiac arrhythmia.
6 citations
,
January 2013 in “Journal of Clinical and Diagnostic Research” This study found that anti-mullerian hormone levels are significantly elevated in infertile women with polycystic ovarian syndrome compared to those with regular cycles, suggesting it as a potential marker for diagnosing PCOS-related infertility.
5 citations
,
October 2021 in “Signal Transduction and Targeted Therapy” In this study, structural and functional brain abnormalities specific to visuospatial and somatosensory processing networks were observed in patients with anorexia nervosa, highlighting a critical role for the precuneus.
3 citations
,
February 2017 in “Archives of Medical Science” This study found that finasteride treatment in male rats may lead to changes in connexin 43 expression in the testes of their offspring, potentially affecting spermatogenesis.
3 citations
,
December 2013 in “Balkan Journal of Medical Genetics” This case report highlights the use of microarray analysis to identify cryptic chromosomal rearrangements in a young woman with intellectual disability and multiple congenital anomalies.
1 citations
,
December 2023 in “Scientific reports” This study investigated the use of 3D cell culture technology to explore hair follicle regeneration, examining the impact of the 3D cellular environment on hair follicle morphogenesis and the effects of microwell depth on spheroid formation.
1 citations
,
October 2023 in “Veterinary Dermatology” This study found that in Pomeranian dogs with alopecia X, dermoscopic evaluations can supplement diagnoses, and transverse skin biopsy sections better assess hair follicle density and identify growth arrest phases compared to longitudinal sections.
1 citations
,
September 2023 in “Life science alliance” In this study, researchers observed that Vdr-knockout mice experience hair cycle arrest during the catagen stage, leading to alopecia, with persistent epithelial strands forming in the hair follicles, indicating Vitamin D receptor's role in regulating hair follicle regression and regeneration.
1 citations
,
January 2019 in “Przegla̧d dermatologiczny” This article reviews the concept of cardiodermatology and its application in clinical practice but does not present new empirical findings.
1 citations
,
December 2013 in “BMJ case reports” This case report describes a 27-year-old pregnant woman with Werner9s syndrome and uncontrolled hypertension, resulting in her death during an emergency caesarean section, though her baby survived and tested negative for the condition.
1 citations
,
January 2011 in “Journal of Human Reproductive Sciences” Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.
1 citations
,
January 1997 in “Skin Pharmacology and Physiology” In this study, researchers found a significant decrease in the modulus of elasticity of hair shafts in premature neonates compared to full-term ones, potentially due to differences in disulphide bonds or microfibril arrangement.
July 2026 in “Nature Communications” This study reports that brief exposure to low intensity and low frequency ultrasound was able to transiently break cellular microtubules and mitigate hair follicle damage, suggesting a potential method to prevent hair loss during chemotherapy with taxanes like paclitaxel.
October 2025 in “Journal of Translational Medicine” This literature review discusses the challenges and potential strategies for creating fully functional hair follicles capable of active cycling, emphasizing the molecular mechanisms, signaling pathways, and innovative regenerative techniques, such as hair micropatterning and three-dimensional printing, crucial for optimizing hair follicle regeneration.
September 2025 in “Arthritis Research & Therapy” In this study, researchers found that the compound BMS-470539 induced a senescence-like state in fibroblasts from systemic sclerosis patients, reducing fibrosis-associated markers in vitro and decreasing skin thickness in a mouse model of skin fibrosis, suggesting a novel therapeutic strategy for managing fibroblast-driven diseases.
August 2025 in “Anais Brasileiros de Dermatologia” This review details phenol's dermatological uses and underscores its potent skin rejuvenation effects but emphasizes the need for caution due to risks of serious complications, including cardiac arrhythmias and organ failure, particularly with improper use or large-area applications.