Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that adding sheep wool to soil can increase water retention and delay drought stress in red clover, although further research is needed to confirm these effects under field conditions.

This review synthesizes current knowledge on choriogenesis, the final stage of oogenesis in insects, by exploring the role of follicle cells, regulatory mechanisms of gene expression, and the biochemical makeup of the eggshell, while also highlighting structural diversity and adaptations across insect species.

This review highlights how engineered hydrogels can modulate immune niches and serve as in vivo models to study them, noting collaboration is needed to advance therapeutic outcomes.

This study found that fibroblast growth factors exhibit significant expression differences in the skin of rodents and primates, which may be linked to their evolutionary and environmental adaptations.

In this study, researchers propose that the EDAR V370A allele's positive selection in East Asian populations may be linked to stable aquatic resources from Late Pleistocene ecosystems in northern China, suggesting a "nutritional niche construction" framework where these resources offset the allele's metabolic costs.

This study presents a hypothesis that the EDAR V370A allele was positively selected in East Asian populations due to the stable aquatic resources in Late Pleistocene northern China, which may have offset the allele's metabolic costs and provided a selective advantage.

This study found that COVID-19 infection disrupts spermatogenesis, alters testicular cell populations, and may impact male fertility by causing long-term changes in testicular function and reduced sperm quality, as observed even in patients who have recovered from the acute phase of the infection.

This study provides a framework for understanding different types of alopecias based on immune privilege collapse at specific follicular sites, revealing distinct patterns in immune effector programs and stromal influences depending on the alopecia type.

In this study, a computational analysis of promoter regions in human fertility-related genes identified several new candidate regulatory motifs, but these require further experimental validation due to the limitations of being an in silico examination.

This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.

This study found that integrating Lactobacillus-rich probiotic nutrition and fractional CO₂ laser therapy with clotrimazole in mucoadhesive hydrogels significantly improved clinical and structural outcomes for women with recurrent vulvovaginal candidiasis, suggesting a promising advanced therapy, though further validation in larger trials is needed.

This review highlights how chronic inflammatory skin disorders like psoriasis and atopic dermatitis may be better understood as manifestations of systemic immune dysregulation rather than just skin issues, suggesting that recognizing these conditions as markers of broader immune imbalance can improve diagnosis and medical education.

This study suggests that fibroblast growth factors exhibit significant expression differences in rodent and primate skin, potentially related to their evolutionary paths and environmental adaptations.

This study describes an adaptive hair extension method designed to improve comfort, durability, and aesthetics, based on analysis of hypothetical client profiles and their biomechanical tolerance.

This review explores advancements in bioprinting technologies for developing in vitro skin models that replicate immune-mediated skin diseases, highlighting their potential to reduce animal testing and enhance research and product testing capabilities in dermatology.

This study found that both dark and white dromedary camels exhibited high medullation in hair fibers, suggesting adaptations for insulation and heat dissipation in hot desert environments.

In this study, researchers developed an axolotl skin-derived extracellular matrix scaffold that enhanced wound healing in mice by promoting skin regeneration and reducing fibrosis, offering potential as a regenerative biomaterial for clinical use.

This study developed a partially automated protocol utilizing hair follicles for DNA extraction in marmosets, achieving reliable whole genome sequencing with low chimerism, offering an efficient alternative to blood for genetic studies in non-human primates.

In this study, researchers developed a non-invasive, partially automated protocol for extracting DNA from marmoset hair follicles, resulting in high-quality whole genome sequencing with low chimerism levels, making it a reliable method compared to blood DNA sequencing in these primates.

This study examined molecular predictors of ritlecitinib efficacy in treating alopecia areata, highlighting the role of JAK3-dependent inflammation and follicular integrity as important factors in understanding disease mechanisms and potential therapeutic effectiveness.

This study found that exosomes from human umbilical cord mesenchymal stem cells significantly promoted hair follicle growth and enhanced the transition to the growth phase in a model of androgenetic alopecia, by enriching specific microRNAs that activate key pathways involved in hair regeneration.

This study found that peimine treatment significantly improved wound healing and tissue regeneration in mice by enhancing wound closure, granulation tissue formation, and epidermal thickness, with effects linked to activation of the Notch1 signaling pathway.

This literature review highlights recent advancements in hair follicle regeneration techniques, noting the potential of combining stem cell technology, 3D bioprinting, and epigenetic modulation to create precision therapies. However, it emphasizes ongoing challenges such as achieving long-term viability and scalability for clinical application.

In this study, loss of the Notch ligand Jag2 in mouse epidermal cells disrupted early differentiation and affected the structure and behavior of adjacent melanocytes, highlighting Jag2's role in epidermal differentiation and tissue homeostasis.

Reducing neutrophils or inhibiting NETs improves wound healing in sickle cell disease.

In this study, UVB irradiation increased mast cell degranulation only when skin was innervated, suggesting that the interaction between mast cells and nerve fibres may exacerbate solar elastosis by promoting dysfunctional dermal elastic fiber accumulation, but further research is needed for confirmation.

This study found significant genetic differences between pigs with and without hair whorls, suggesting potential implications for pig breeding strategies in China.

This study used atomic force microscopy to identify significant morphological differences in hair from patients with lichen planopilaris compared to healthy controls, noting more scratches, uneven edges, and pitted scales in affected hair, which may aid future research on the condition.

In this study, researchers observed that graded calorie restriction in mice led to changes in stable isotope ratios and elemental content in bone collagen and hair keratin, potentially indicating intensified mobilization of endogenous proteins and altered bone collagen structure with increased dietary stress.

In a keratinocyte-specific knockout mouse model, this study found that deleting GRK2 disrupted hair follicle homeostasis, causing cyst-like structures, abnormal growth patterns, and eventual hair loss, suggesting potential links to immune-mediated alopecias.