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Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Androgens prevent hair growth by changing Wnt signals in cells.

Sex hormones affect brain injury differently in males and females.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Hsc70 protein may influence hair growth by responding to androgens.

COVID-19 may worsen with androgens; anti-androgen drugs could help.

New compounds may help treat prostate cancer by reducing cell growth.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Testosterone may slow down wound healing and increase inflammation.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.