Search

everythinglearnresearchcommunity

for

Search:↓

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

The Hairless gene is crucial for healthy skin and hair growth.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Mice with human gene experienced hair loss when treated with DHT.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Dutasteride and finasteride affect different cell types differently.

Certain gene variations are linked to better memory in healthy Chinese women.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Minoxidil can reduce functions related to androgen receptors.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Skin cancer often starts from Lgr5+ progenitor cells.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.