2 citations
,
September 2002 in “Dermatologic Surgery” This study describes how arrector pili muscles form a single muscular structure shared by all hair follicles within a follicular unit at the isthmus level in scalp skin.
8 citations
,
April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
2 citations
,
March 2025 in “International Journal of Advanced Science and Engineering” This review highlights that nanoemulsions, especially those with droplet sizes under 200 nm, show promise in pharmaceuticals and cosmetics by improving drug stability, bioavailability, and reducing side effects, with potential applications in CNS diseases, cancer treatments, and skincare products.
1 citations
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November 2025 in “Clinical and Experimental Medicine” This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that AP-2α and AP-2β transcription factors are crucial for maintaining adult skin homeostasis, with their inactivation in keratinocytes leading to impaired differentiation, hair abnormalities, and inflammation, highlighting their key regulatory roles.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
16 citations
,
March 2018 in “Seminars in Oncology” This article compares the immunology of cancer and the placenta and suggests that immunotherapy for pregnant cancer patients could be feasible with careful exploration, though no new clinical results are reported.
4 citations
,
May 2021 in “Biomedicines” This review explores the potential role of caveolin-1 in cicatricial alopecia, particularly frontal fibrosing alopecia, and discusses possibilities for targeted therapies without providing new research results.
1 citations
,
August 2024 in “Transgenic Research” In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.
December 2025 in “International Journal of Therapeutic Innovation.” This study developed an herbal hair mask using natural ingredients like rice water, aloe vera gel, and coconut oil, which demonstrated moisturizing, strengthening, and protective properties, potentially aiding in maintaining healthy and resilient hair.
March 2024 in “Research Square (Research Square)” This study found no significant benefit of platelet-rich plasma injections over placebo in improving erectile function in patients with mild to moderate erectile dysfunction.
January 2020 in “Research Square (Research Square)” In this study, Irish adults with severe obesity who had cervical or axillary skin tags showed higher systolic blood pressure, higher HbA1c levels, and more diabetes and hypertension, suggesting an increased vascular risk.
December 2018 in “Progress in Medical Sciences” This study observed that methanol extract of Phoenix dactilifera improved kidney function in rats at 4 and 8 mg/kg doses, but a 16 mg/kg dose may impair kidney function by affecting urea and potassium excretion.
35 citations
,
March 2014 in “British Journal of Dermatology” This study found that in androgenic alopecia, the arrector pili muscle degenerates and is replaced by fat, unlike in normal skin or telogen effluvium.
50 citations
,
November 2010 in “Plastic and Reconstructive Surgery” This study suggests that Botox injections may increase hair count and reduce hair loss in men with androgenetic alopecia, potentially through increased blood flow and oxygen to the scalp.
19 citations
,
April 2015 in “Stem Cells” This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.
24 citations
,
June 2012 in “BMC Research Notes” This study outlines the Human Gene Correlation Analysis tool, which classifies human genes by coexpression levels and identifies overrepresented annotation terms in correlated gene groups, with no new clinical results reported.
22 citations
,
July 2012 in “International Journal of Trichology” This study found that loss of contact between the arrector pili muscle and the hair follicle bulge may explain why hair loss in male and female pattern baldness is largely irreversible, unlike in alopecia areata.
November 2017 in “Dermatologic Therapy” This study reports that a new topical solution, AB-102, containing a high concentration of a weak α1 agonist, significantly reduces hair shedding during brushing by up to 77% without causing cardiac or hemodynamic adverse events.
11 citations
,
March 2020 in “American Journal of Medical Genetics Part A” This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.
In this study, researchers observed that individuals with acne vulgaris in the Qassim Region of Saudi Arabia had a significantly higher rate of vitamin B12 deficiency, suggesting a potential association that warrants further investigation.
49 citations
,
July 2004 in “Anesthesiology” This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
15 citations
,
January 2020 in “BioMed Research International” In this study of patients with androgenetic alopecia, botulinum toxin type A was found to significantly increase hair counts and improve hair density and coverage, with enhanced results observed when combined with oral finasteride, revealing a safe and effective treatment approach without adverse effects.
November 2023 in “Global journal of medical research” This study highlights the importance of understanding the rheological properties of hyaluronic acid fillers, including viscosity, cross-linking, and concentration, to optimize their use in addressing facial aging by maximizing clinical effects.
100 citations
,
July 2018 in “Journal of The American Academy of Dermatology” This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.
9 citations
,
January 2023 in “Cellular and Molecular Life Sciences” This study found that intrauterine administration of botulinum toxin A improved endometrial environment and receptivity in a murine model of thin endometrium through mechanisms involving IGFBP3 and osteopontin.
333 citations
,
February 2010 in “Cell Stem Cell” This review discusses experimental data, technologies, and genetic factors related to stem cell niches, highlighting their role in tissue regeneration and diseases, but reports no new results.
33 citations
,
November 1994 in “Archives of Biochemistry and Biophysics”
26 citations
,
August 2014 in “Genetic Testing and Molecular Biomarkers” This study suggests that the TNF-α system may contribute to hyperandrogenism, obesity, and insulin resistance in polycystic ovarian syndrome, independent of the C850T polymorphism.
12 citations
,
March 2018 in “Bioengineering” This review discusses the use of non-transfusional hemocomponents in surgical procedures for tissue regeneration and reports no new empirical findings.